Regioselective Markovnikov hydrodifluoroalkylation of alkenes using difluoroenoxysilanes
Alkene hydrodifluoroalkylation is a fruitful strategy for synthesizing medicinally relevant difluoromethylated molecules. Here, the authors report a Markovnikov hydrodifluoroalkylation of aryl and aliphatic alkenes using inexpensive Mg(ClO4)2·6H2O as catalyst and difluoroenoxysilanes as the nucleoph...
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Autores principales: | Xiao-Si Hu, Jun-Xiong He, Su-Zhen Dong, Qiu-Hua Zhao, Jin-Sheng Yu, Jian Zhou |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/e4d4b12b453c48aab89439a02d903c32 |
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