Self-amplification of oxidative stress with tumour microenvironment-activatable iron-doped nanoplatform for targeting hepatocellular carcinoma synergistic cascade therapy and diagnosis
Abstract Background Hepatocellular carcinoma is insensitive to many chemotherapeutic agents. Ferroptosis is a form of programmed cell death with a Fenton reaction mechanism. It converts endogenous hydrogen peroxide into highly toxic hydroxyl radicals, which inhibit hepatocellular carcinoma progressi...
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Autores principales: | Qiao-Mei Zhou, Yuan-Fei Lu, Jia-Ping Zhou, Xiao-Yan Yang, Xiao-Jie Wang, Jie-Ni Yu, Yong-Zhong Du, Ri-Sheng Yu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
BMC
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/e4d630bf084040b895b06c2b4b80c206 |
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