Experience-dependent structural plasticity targets dynamic filopodia in regulating dendrite maturation and synaptogenesis

During development, dendrites display structural plasticity, as reflected in the appearance of long, thin and highly motile dendritic filopodia. Here, the authors examine dendritic dynamics of ventral lateral neurons in the developing Drosophila larva, and identify Amphiphysin as an important regula...

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Bibliographic Details
Main Authors: Chengyu Sheng, Uzma Javed, Mary Gibbs, Caixia Long, Jun Yin, Bo Qin, Quan Yuan
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/e4dcd6c1a5bb4c4c8ac826aaf1e082f6
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Summary:During development, dendrites display structural plasticity, as reflected in the appearance of long, thin and highly motile dendritic filopodia. Here, the authors examine dendritic dynamics of ventral lateral neurons in the developing Drosophila larva, and identify Amphiphysin as an important regulator of this process.