Human PrimPol activity is enhanced by RPA

Abstract Human PrimPol is a primase belonging to the AEP superfamily with the unique ability to synthesize DNA primers de novo, and a non-processive DNA polymerase able to bypass certain DNA lesions. PrimPol facilitates both mitochondrial and nuclear replication fork progression either acting as a c...

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Auteurs principaux: María I. Martínez-Jiménez, Antonio Lahera, Luis Blanco
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/e4e0ed8466c843938886b4e3fd80fbc5
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