Widespread bacterial lysine degradation proceeding via glutarate and L-2-hydroxyglutarate

Lysine degradation and the role of the metabolites glutarate and L-2-hydroxyglutarate have remained elusive in many organisms including Escherichia coli. Here authors present a pathway for catabolism of lysine to succinate in E. coli involving glutarate and L-2-hydroxyglutarate as intermediates.

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Bibliographic Details
Main Authors: Sebastian Knorr, Malte Sinn, Dmitry Galetskiy, Rhys M. Williams, Changhao Wang, Nicolai Müller, Olga Mayans, David Schleheck, Jörg S. Hartig
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/e4e3b0c443c147f993908177af49c611
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