Human adenovirus type 8 epidemic keratoconjunctivitis with large corneal epithelial full-layer detachment: an endemic outbreak with uncommon manifestations

Yueh-Chang Lee,1 Nancy Chen,1 I-Tsong Huang,2–4 Hui-Hua Yang,2 Chin-Te Huang,1 Li-Kuang Chen,2–5 Min-Muh Sheu1,6,7 1Department of Ophthalmology, 2Taiwan CDC Collaborating Laboratories of Virology, 3Department of Laboratory Medicine, Buddhist Tzu-Chi General Hospital, Hualien, Ta...

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Autores principales:	Lee YC, Chen N, Huang IT, Yang HH, Huang CT, Chen LK, Sheu MM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/e4e55d345b50496c82e0a7625a2f628f
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spelling	oai:doaj.org-article:e4e55d345b50496c82e0a7625a2f628f2021-12-02T02:13:19ZHuman adenovirus type 8 epidemic keratoconjunctivitis with large corneal epithelial full-layer detachment: an endemic outbreak with uncommon manifestations1177-5483https://doaj.org/article/e4e55d345b50496c82e0a7625a2f628f2015-05-01T00:00:00Zhttp://www.dovepress.com/human-adenovirus-type-8-epidemic-keratoconjunctivitis-with-large-corne-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Yueh-Chang Lee,1 Nancy Chen,1 I-Tsong Huang,2–4 Hui-Hua Yang,2 Chin-Te Huang,1 Li-Kuang Chen,2–5 Min-Muh Sheu1,6,7 1Department of Ophthalmology, 2Taiwan CDC Collaborating Laboratories of Virology, 3Department of Laboratory Medicine, Buddhist Tzu-Chi General Hospital, Hualien, Taiwan; 4Graduate Institute of Medical Sciences, 5Department of Laboratory Diagnosis, 6Department of Ophthalmology and Visual Science, Tzu-Chi University, Hualien, Taiwan; 7Department of Ophthalmology, Mennonite Christian Hospital, Hualien, Taiwan Abstract: Epidemic viral conjunctivitis is a highly contagious disease that is encountered year-round. The causative agents are mainly adenoviruses and enteroviruses. It occurs most commonly upon infection with subgroup D adenoviruses of types 8, 19, or 37. For common corneal involvement of human adenovirus type 8 epidemic keratoconjunctivitis, full-layer epithelial detachment is rarely seen. Herein, we report three cases of epidemic keratoconjunctivitis during an outbreak which manifested as large corneal epithelial full-layer detachment within a few days. The lesions healed without severe sequelae under proper treatment. The unique manifestation of this outbreak may indicate the evolution of human adenovirus type 8. Keywords: EKC, HAdV-8, cornea, virology, epidemic viral conjunctivitisLee YCChen NHuang ITYang HHHuang CTChen LKSheu MMDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 953-957 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Lee YC Chen N Huang IT Yang HH Huang CT Chen LK Sheu MM Human adenovirus type 8 epidemic keratoconjunctivitis with large corneal epithelial full-layer detachment: an endemic outbreak with uncommon manifestations
description	Yueh-Chang Lee,1 Nancy Chen,1 I-Tsong Huang,2–4 Hui-Hua Yang,2 Chin-Te Huang,1 Li-Kuang Chen,2–5 Min-Muh Sheu1,6,7 1Department of Ophthalmology, 2Taiwan CDC Collaborating Laboratories of Virology, 3Department of Laboratory Medicine, Buddhist Tzu-Chi General Hospital, Hualien, Taiwan; 4Graduate Institute of Medical Sciences, 5Department of Laboratory Diagnosis, 6Department of Ophthalmology and Visual Science, Tzu-Chi University, Hualien, Taiwan; 7Department of Ophthalmology, Mennonite Christian Hospital, Hualien, Taiwan Abstract: Epidemic viral conjunctivitis is a highly contagious disease that is encountered year-round. The causative agents are mainly adenoviruses and enteroviruses. It occurs most commonly upon infection with subgroup D adenoviruses of types 8, 19, or 37. For common corneal involvement of human adenovirus type 8 epidemic keratoconjunctivitis, full-layer epithelial detachment is rarely seen. Herein, we report three cases of epidemic keratoconjunctivitis during an outbreak which manifested as large corneal epithelial full-layer detachment within a few days. The lesions healed without severe sequelae under proper treatment. The unique manifestation of this outbreak may indicate the evolution of human adenovirus type 8. Keywords: EKC, HAdV-8, cornea, virology, epidemic viral conjunctivitis
format	article
author	Lee YC Chen N Huang IT Yang HH Huang CT Chen LK Sheu MM
author_facet	Lee YC Chen N Huang IT Yang HH Huang CT Chen LK Sheu MM
author_sort	Lee YC
title	Human adenovirus type 8 epidemic keratoconjunctivitis with large corneal epithelial full-layer detachment: an endemic outbreak with uncommon manifestations
title_short	Human adenovirus type 8 epidemic keratoconjunctivitis with large corneal epithelial full-layer detachment: an endemic outbreak with uncommon manifestations
title_full	Human adenovirus type 8 epidemic keratoconjunctivitis with large corneal epithelial full-layer detachment: an endemic outbreak with uncommon manifestations
title_fullStr	Human adenovirus type 8 epidemic keratoconjunctivitis with large corneal epithelial full-layer detachment: an endemic outbreak with uncommon manifestations
title_full_unstemmed	Human adenovirus type 8 epidemic keratoconjunctivitis with large corneal epithelial full-layer detachment: an endemic outbreak with uncommon manifestations
title_sort	human adenovirus type 8 epidemic keratoconjunctivitis with large corneal epithelial full-layer detachment: an endemic outbreak with uncommon manifestations
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/e4e55d345b50496c82e0a7625a2f628f
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Human adenovirus type 8 epidemic keratoconjunctivitis with large corneal epithelial full-layer detachment: an endemic outbreak with uncommon manifestations

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