iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications

The Cre-Lox system allows high spatiotemporal control of genetic modifications. Here the authors present iSuRe-Cre that significantly increases Cre activity in reporter expressing cells, which ultimately increases the efficiency and reliability of Cre-dependent reporter and gene function analysis.

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Autores principales:	Macarena Fernández-Chacón, Verónica Casquero-García, Wen Luo, Federica Francesca Lunella, Susana Ferreira Rocha, Sergio Del Olmo-Cabrera, Rui Benedito
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e50289266aca4746824f4bb0ef51b537
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spelling	oai:doaj.org-article:e50289266aca4746824f4bb0ef51b5372021-12-02T16:58:04ZiSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications10.1038/s41467-019-10239-42041-1723https://doaj.org/article/e50289266aca4746824f4bb0ef51b5372019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10239-4https://doaj.org/toc/2041-1723The Cre-Lox system allows high spatiotemporal control of genetic modifications. Here the authors present iSuRe-Cre that significantly increases Cre activity in reporter expressing cells, which ultimately increases the efficiency and reliability of Cre-dependent reporter and gene function analysis.Macarena Fernández-ChacónVerónica Casquero-GarcíaWen LuoFederica Francesca LunellaSusana Ferreira RochaSergio Del Olmo-CabreraRui BeneditoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Macarena Fernández-Chacón Verónica Casquero-García Wen Luo Federica Francesca Lunella Susana Ferreira Rocha Sergio Del Olmo-Cabrera Rui Benedito iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications
description	The Cre-Lox system allows high spatiotemporal control of genetic modifications. Here the authors present iSuRe-Cre that significantly increases Cre activity in reporter expressing cells, which ultimately increases the efficiency and reliability of Cre-dependent reporter and gene function analysis.
format	article
author	Macarena Fernández-Chacón Verónica Casquero-García Wen Luo Federica Francesca Lunella Susana Ferreira Rocha Sergio Del Olmo-Cabrera Rui Benedito
author_facet	Macarena Fernández-Chacón Verónica Casquero-García Wen Luo Federica Francesca Lunella Susana Ferreira Rocha Sergio Del Olmo-Cabrera Rui Benedito
author_sort	Macarena Fernández-Chacón
title	iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications
title_short	iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications
title_full	iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications
title_fullStr	iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications
title_full_unstemmed	iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications
title_sort	isure-cre is a genetic tool to reliably induce and report cre-dependent genetic modifications
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/e50289266aca4746824f4bb0ef51b537
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iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications

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