Broad-spectrum kinetic resolution of alcohols enabled by Cu–H-catalysed dehydrogenative coupling with hydrosilanes
Kinetic resolution of alcohols by silylation is an attractive method to produce enantiopure compounds, but known systems often display limited substrate scope. Here the authors report a copper catalysed enantioselective dehydrogenative silylation of alcohols that have high selectivity across a broad...
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Autores principales: | Xichang Dong, Andreas Weickgenannt, Martin Oestreich |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/e506d0b7d1b545dcbd08d7a705017f56 |
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