Characterizing the distributions of IDO-1 expressing macrophages/microglia in human and murine brains and evaluating the immunological and physiological roles of IDO-1 in RAW264.7/BV-2 cells
Indoleamine 2,3-dioxygenase 1 (IDO-1) is an immunosuppressive enzyme expressed in the placenta, neoplastic cells, and macrophages to reject T cells by converting tryptophan into kynurenine. However, the role of IDO-1 in brain immunity, especially in the meninges, is unclear. We aim to elucidate the...
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| Lenguaje: | EN |
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Public Library of Science (PLoS)
2021
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| Acceso en línea: | https://doaj.org/article/e515c59e094e4bcf9dc159a7e07523d9 |
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por Rong Ji, Lixiang Ma, Xinyu Chen, Renqiang Sun, Li Zhang, Hexige Saiyin, Wenshi Wei
Publicado 2021
Enlace del recursoPublicado 2021
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