Magneto-nanosensor platform for probing low-affinity protein–protein interactions and identification of a low-affinity PD-L1/PD-L2 interaction

Magneto-nanosensor platform for probing low-affinity protein–protein interactions and identification of a low-affinity PD-L1/PD-L2 interaction

Measurement of low-affinity protein–protein interactions is challenging; surface plasmon resonance requires high concentrations of reagents. Here the authors combine magneto-nanosensors with microfluidic chips and protein-conjugated magnetic nanoparticles to discover a low-affinity interaction betwe...

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Autores principales: Jung-Rok Lee, Daniel J. B. Bechstein, Chin Chun Ooi, Ashka Patel, Richard S. Gaster, Elaine Ng, Lino C. Gonzalez, Shan X. Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/e5190858f2fc4fbaa809b26cb3ad4f36
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