High-intensity interval training induces a modest systemic inflammatory response in active, young men

Kevin A Zwetsloot,1 Casey S John,1 Marcus M Lawrence,1 Rebecca A Battista,1 R Andrew Shanely1,2 1Department of Health, Leisure, and Exercise Science, Appalachian State University, Boone, NC, USA; 2Human Performance Laboratory, North Carolina Research Campus, Appalachian State University, Kannapolis...

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Autores principales:	Zwetsloot KA, John CS, Lawrence MM, Battista RA, Shanely RA
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Pathology RB1-214 Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/e51efdb7f9b0488e802e6deb9c957825
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spelling	oai:doaj.org-article:e51efdb7f9b0488e802e6deb9c9578252021-12-02T05:52:43ZHigh-intensity interval training induces a modest systemic inflammatory response in active, young men1178-7031https://doaj.org/article/e51efdb7f9b0488e802e6deb9c9578252014-01-01T00:00:00Zhttp://www.dovepress.com/high-intensity-interval-training-induces-a-modest-systemic-inflammator-a15463https://doaj.org/toc/1178-7031 Kevin A Zwetsloot,1 Casey S John,1 Marcus M Lawrence,1 Rebecca A Battista,1 R Andrew Shanely1,2 1Department of Health, Leisure, and Exercise Science, Appalachian State University, Boone, NC, USA; 2Human Performance Laboratory, North Carolina Research Campus, Appalachian State University, Kannapolis, NC, USA Abstract: The purpose of this study was to determine: 1) the extent to which an acute session of high-intensity interval training (HIIT) increases systemic inflammatory cytokines and chemokines, and 2) whether 2 weeks of HIIT training alters the inflammatory response. Eight recreationally active males (aged 22±2 years) performed 2 weeks of HIIT on a cycle ergometer (six HIIT sessions at 8–12 intervals; 60-second intervals, 75-second active rest) at a power output equivalent to 100% of their predetermined peak oxygen uptake (VO2max). Serum samples were collected during the first and sixth HIIT sessions at rest and immediately, 15, 30, and 45 minutes post-exercise. An acute session of HIIT induced significant increases in interleukin (IL)-6, IL-8, IL-10, tumor necrosis factor-α, and monocyte chemotactic protein-1 compared with rest. The concentrations of interferon-γ, granulocyte macrophage-colony-stimulating factor, and IL-1β were unaltered with an acute session of HIIT. Two weeks of training did not alter the inflammatory response to an acute bout of HIIT exercise. Maximal power achieved during a VO2max test significantly increased 4.6%, despite no improvements in VO2max after 2 weeks of HIIT. These data suggest that HIIT exercise induces a small inflammatory response in young, recreationally active men; however, 2 weeks of HIIT does not alter this response. Keywords: cycle ergometer, inflammatory cytokines, exercise trainingZwetsloot KAJohn CSLawrence MMBattista RAShanely RADove Medical PressarticlePathologyRB1-214Therapeutics. PharmacologyRM1-950ENJournal of Inflammation Research, Vol 2014, Iss default, Pp 9-17 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Pathology RB1-214 Therapeutics. Pharmacology RM1-950
spellingShingle	Pathology RB1-214 Therapeutics. Pharmacology RM1-950 Zwetsloot KA John CS Lawrence MM Battista RA Shanely RA High-intensity interval training induces a modest systemic inflammatory response in active, young men
description	Kevin A Zwetsloot,1 Casey S John,1 Marcus M Lawrence,1 Rebecca A Battista,1 R Andrew Shanely1,2 1Department of Health, Leisure, and Exercise Science, Appalachian State University, Boone, NC, USA; 2Human Performance Laboratory, North Carolina Research Campus, Appalachian State University, Kannapolis, NC, USA Abstract: The purpose of this study was to determine: 1) the extent to which an acute session of high-intensity interval training (HIIT) increases systemic inflammatory cytokines and chemokines, and 2) whether 2 weeks of HIIT training alters the inflammatory response. Eight recreationally active males (aged 22±2 years) performed 2 weeks of HIIT on a cycle ergometer (six HIIT sessions at 8–12 intervals; 60-second intervals, 75-second active rest) at a power output equivalent to 100% of their predetermined peak oxygen uptake (VO2max). Serum samples were collected during the first and sixth HIIT sessions at rest and immediately, 15, 30, and 45 minutes post-exercise. An acute session of HIIT induced significant increases in interleukin (IL)-6, IL-8, IL-10, tumor necrosis factor-α, and monocyte chemotactic protein-1 compared with rest. The concentrations of interferon-γ, granulocyte macrophage-colony-stimulating factor, and IL-1β were unaltered with an acute session of HIIT. Two weeks of training did not alter the inflammatory response to an acute bout of HIIT exercise. Maximal power achieved during a VO2max test significantly increased 4.6%, despite no improvements in VO2max after 2 weeks of HIIT. These data suggest that HIIT exercise induces a small inflammatory response in young, recreationally active men; however, 2 weeks of HIIT does not alter this response. Keywords: cycle ergometer, inflammatory cytokines, exercise training
format	article
author	Zwetsloot KA John CS Lawrence MM Battista RA Shanely RA
author_facet	Zwetsloot KA John CS Lawrence MM Battista RA Shanely RA
author_sort	Zwetsloot KA
title	High-intensity interval training induces a modest systemic inflammatory response in active, young men
title_short	High-intensity interval training induces a modest systemic inflammatory response in active, young men
title_full	High-intensity interval training induces a modest systemic inflammatory response in active, young men
title_fullStr	High-intensity interval training induces a modest systemic inflammatory response in active, young men
title_full_unstemmed	High-intensity interval training induces a modest systemic inflammatory response in active, young men
title_sort	high-intensity interval training induces a modest systemic inflammatory response in active, young men
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/e51efdb7f9b0488e802e6deb9c957825
work_keys_str_mv	AT zwetslootka highintensityintervaltraininginducesamodestsystemicinflammatoryresponseinactiveyoungmen AT johncs highintensityintervaltraininginducesamodestsystemicinflammatoryresponseinactiveyoungmen AT lawrencemm highintensityintervaltraininginducesamodestsystemicinflammatoryresponseinactiveyoungmen AT battistara highintensityintervaltraininginducesamodestsystemicinflammatoryresponseinactiveyoungmen AT shanelyra highintensityintervaltraininginducesamodestsystemicinflammatoryresponseinactiveyoungmen
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High-intensity interval training induces a modest systemic inflammatory response in active, young men

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