3-<i>O</i>-Carbamoyl-5,7,20-<i>O</i>-trimethylsilybins: Synthesis and Preliminary Antiproliferative Evaluation

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3-<i>O</i>-Carbamoyl-5,7,20-<i>O</i>-trimethylsilybins: Synthesis and Preliminary Antiproliferative Evaluation

To search for novel androgen receptor (AR) modulators for the potential treatment of castration-resistant prostate cancer (CRPC), naturally occurring silibinin was sought after as a lead compound because it possesses a moderate potency towards AR-positive prostate cancer cells and its chemical scaff...

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Autores principales:	Sitong Wu, Guanglin Chen, Qiang Zhang, Guangdi Wang, Qiao-Hong Chen
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	silibinin carbamoylation prostate cancer cell proliferation androgen receptor Organic chemistry QD241-441
Acceso en línea:	https://doaj.org/article/e523de46002940f9b5086286570ef89c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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