The Sec63p J-domain is required for ERAD of soluble proteins in yeast.
How misfolded proteins are exported from the ER to the cytosol for degradation (ER-associated Degradation, ERAD) and which proteins are participating in this process is not understood. Several studies using a single, leaky mutant indicated that Sec63p might be involved in ERAD. More recently, Sec63p...
Guardado en:
Autores principales: | Christina Servas, Karin Römisch |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/e5241ed9947846919e346a6d1ddb9377 |
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