Effect of dexamethasone, ketoprofen and cold compress on postoperative sequelae in mandibular third molar surgery: A randomized clinical trial

Purpose: This is a single blinded, randomized clinical trial to assess and compare the effect of dexamethasone, icepack and ketoprofen on the postoperative pain, swelling and trismus following surgical removal of impacted lower third molar (ILTM). Methodology: Consecutive patients who require surgic...

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Autores principales:	Ibrahim Kayode Suleiman, Olutayo James, Hector Oladapo Olasoji
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2022
Materias:	Third molar Postoperative sequelae Dexamethasone Icepack Ketoprofen Internal medicine RC31-1245 Surgery RD1-811
Acceso en línea:	https://doaj.org/article/e537bc04704c4dcdba4ae0cec330eede
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spelling	oai:doaj.org-article:e537bc04704c4dcdba4ae0cec330eede2021-11-06T04:43:06ZEffect of dexamethasone, ketoprofen and cold compress on postoperative sequelae in mandibular third molar surgery: A randomized clinical trial2667-147610.1016/j.adoms.2021.100211https://doaj.org/article/e537bc04704c4dcdba4ae0cec330eede2022-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2667147621002004https://doaj.org/toc/2667-1476Purpose: This is a single blinded, randomized clinical trial to assess and compare the effect of dexamethasone, icepack and ketoprofen on the postoperative pain, swelling and trismus following surgical removal of impacted lower third molar (ILTM). Methodology: Consecutive patients who require surgical extraction of ILTM with a modified Pederson difficulty index score of 5-6 were recruited. Ninety patients were randomly allocated into 3 groups. Group A received 100mg of ketoprofen and group C received 8mg of dexamethasone per-oral 1hr preoperatively. Subjects in group B used a pre-standardized ice pack held against the skin over the angle of the mandible for 6 hours postoperatively. Swelling, trismus and pain were recorded on postoperative day 1, 2 and 7. Result: A total of 78 subjects with mean age of 27.8 ± 4.9 years comprising of 59.0% males completed the study. There were no statistically significant difference found in the sociodemographics. Subjects in the dexamethasone group showed a significant reduction in pain on postoperative day 1 and 2, and in swelling on all postoperative days in review. Conclusion: Oral dexamethasone showed superior reduction in postoperative pain and swelling after ILTM surgery. It also offers an effective, painless, easy route of administration and single dose safety profile. However, icepack provides a low-cost option and may be of importance in low resource settings or in patients allergic to dexamethasone.Ibrahim Kayode SuleimanOlutayo JamesHector Oladapo OlasojiElsevierarticleThird molarPostoperative sequelaeDexamethasoneIcepackKetoprofenInternal medicineRC31-1245SurgeryRD1-811ENAdvances in Oral and Maxillofacial Surgery, Vol 5, Iss , Pp 100211- (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	Third molar Postoperative sequelae Dexamethasone Icepack Ketoprofen Internal medicine RC31-1245 Surgery RD1-811
spellingShingle	Third molar Postoperative sequelae Dexamethasone Icepack Ketoprofen Internal medicine RC31-1245 Surgery RD1-811 Ibrahim Kayode Suleiman Olutayo James Hector Oladapo Olasoji Effect of dexamethasone, ketoprofen and cold compress on postoperative sequelae in mandibular third molar surgery: A randomized clinical trial
description	Purpose: This is a single blinded, randomized clinical trial to assess and compare the effect of dexamethasone, icepack and ketoprofen on the postoperative pain, swelling and trismus following surgical removal of impacted lower third molar (ILTM). Methodology: Consecutive patients who require surgical extraction of ILTM with a modified Pederson difficulty index score of 5-6 were recruited. Ninety patients were randomly allocated into 3 groups. Group A received 100mg of ketoprofen and group C received 8mg of dexamethasone per-oral 1hr preoperatively. Subjects in group B used a pre-standardized ice pack held against the skin over the angle of the mandible for 6 hours postoperatively. Swelling, trismus and pain were recorded on postoperative day 1, 2 and 7. Result: A total of 78 subjects with mean age of 27.8 ± 4.9 years comprising of 59.0% males completed the study. There were no statistically significant difference found in the sociodemographics. Subjects in the dexamethasone group showed a significant reduction in pain on postoperative day 1 and 2, and in swelling on all postoperative days in review. Conclusion: Oral dexamethasone showed superior reduction in postoperative pain and swelling after ILTM surgery. It also offers an effective, painless, easy route of administration and single dose safety profile. However, icepack provides a low-cost option and may be of importance in low resource settings or in patients allergic to dexamethasone.
format	article
author	Ibrahim Kayode Suleiman Olutayo James Hector Oladapo Olasoji
author_facet	Ibrahim Kayode Suleiman Olutayo James Hector Oladapo Olasoji
author_sort	Ibrahim Kayode Suleiman
title	Effect of dexamethasone, ketoprofen and cold compress on postoperative sequelae in mandibular third molar surgery: A randomized clinical trial
title_short	Effect of dexamethasone, ketoprofen and cold compress on postoperative sequelae in mandibular third molar surgery: A randomized clinical trial
title_full	Effect of dexamethasone, ketoprofen and cold compress on postoperative sequelae in mandibular third molar surgery: A randomized clinical trial
title_fullStr	Effect of dexamethasone, ketoprofen and cold compress on postoperative sequelae in mandibular third molar surgery: A randomized clinical trial
title_full_unstemmed	Effect of dexamethasone, ketoprofen and cold compress on postoperative sequelae in mandibular third molar surgery: A randomized clinical trial
title_sort	effect of dexamethasone, ketoprofen and cold compress on postoperative sequelae in mandibular third molar surgery: a randomized clinical trial
publisher	Elsevier
publishDate	2022
url	https://doaj.org/article/e537bc04704c4dcdba4ae0cec330eede
work_keys_str_mv	AT ibrahimkayodesuleiman effectofdexamethasoneketoprofenandcoldcompressonpostoperativesequelaeinmandibularthirdmolarsurgeryarandomizedclinicaltrial AT olutayojames effectofdexamethasoneketoprofenandcoldcompressonpostoperativesequelaeinmandibularthirdmolarsurgeryarandomizedclinicaltrial AT hectoroladapoolasoji effectofdexamethasoneketoprofenandcoldcompressonpostoperativesequelaeinmandibularthirdmolarsurgeryarandomizedclinicaltrial
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Effect of dexamethasone, ketoprofen and cold compress on postoperative sequelae in mandibular third molar surgery: A randomized clinical trial

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