Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour
The role of chemoreceptors on vomeronasal neurons are not fully understood. Here the authors show that in mice, the vomeronasal chemoreceptor Fpr3 responds to peptides from the bacterial MgrB protein, and that exposure to these peptides drives an avoidance response.
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Nature Portfolio
2019
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oai:doaj.org-article:e54176781bf24438a47eaf081f359b202021-12-02T14:38:42ZBacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour10.1038/s41467-019-12842-x2041-1723https://doaj.org/article/e54176781bf24438a47eaf081f359b202019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12842-xhttps://doaj.org/toc/2041-1723The role of chemoreceptors on vomeronasal neurons are not fully understood. Here the authors show that in mice, the vomeronasal chemoreceptor Fpr3 responds to peptides from the bacterial MgrB protein, and that exposure to these peptides drives an avoidance response.Bernd BufeYannick TeuchertAndreas SchmidMartina PyrskiAnabel Pérez-GómezJanina EisenbeisThomas TimmTomohiro IshiiGünter LochnitMarkus BischoffPeter MombaertsTrese Leinders-ZufallFrank ZufallNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019) |
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Science Q Bernd Bufe Yannick Teuchert Andreas Schmid Martina Pyrski Anabel Pérez-Gómez Janina Eisenbeis Thomas Timm Tomohiro Ishii Günter Lochnit Markus Bischoff Peter Mombaerts Trese Leinders-Zufall Frank Zufall Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour |
description |
The role of chemoreceptors on vomeronasal neurons are not fully understood. Here the authors show that in mice, the vomeronasal chemoreceptor Fpr3 responds to peptides from the bacterial MgrB protein, and that exposure to these peptides drives an avoidance response. |
format |
article |
author |
Bernd Bufe Yannick Teuchert Andreas Schmid Martina Pyrski Anabel Pérez-Gómez Janina Eisenbeis Thomas Timm Tomohiro Ishii Günter Lochnit Markus Bischoff Peter Mombaerts Trese Leinders-Zufall Frank Zufall |
author_facet |
Bernd Bufe Yannick Teuchert Andreas Schmid Martina Pyrski Anabel Pérez-Gómez Janina Eisenbeis Thomas Timm Tomohiro Ishii Günter Lochnit Markus Bischoff Peter Mombaerts Trese Leinders-Zufall Frank Zufall |
author_sort |
Bernd Bufe |
title |
Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour |
title_short |
Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour |
title_full |
Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour |
title_fullStr |
Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour |
title_full_unstemmed |
Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour |
title_sort |
bacterial mgrb peptide activates chemoreceptor fpr3 in mouse accessory olfactory system and drives avoidance behaviour |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/e54176781bf24438a47eaf081f359b20 |
work_keys_str_mv |
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