Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour

The role of chemoreceptors on vomeronasal neurons are not fully understood. Here the authors show that in mice, the vomeronasal chemoreceptor Fpr3 responds to peptides from the bacterial MgrB protein, and that exposure to these peptides drives an avoidance response.

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Autores principales: Bernd Bufe, Yannick Teuchert, Andreas Schmid, Martina Pyrski, Anabel Pérez-Gómez, Janina Eisenbeis, Thomas Timm, Tomohiro Ishii, Günter Lochnit, Markus Bischoff, Peter Mombaerts, Trese Leinders-Zufall, Frank Zufall
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/e54176781bf24438a47eaf081f359b20
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spelling oai:doaj.org-article:e54176781bf24438a47eaf081f359b202021-12-02T14:38:42ZBacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour10.1038/s41467-019-12842-x2041-1723https://doaj.org/article/e54176781bf24438a47eaf081f359b202019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12842-xhttps://doaj.org/toc/2041-1723The role of chemoreceptors on vomeronasal neurons are not fully understood. Here the authors show that in mice, the vomeronasal chemoreceptor Fpr3 responds to peptides from the bacterial MgrB protein, and that exposure to these peptides drives an avoidance response.Bernd BufeYannick TeuchertAndreas SchmidMartina PyrskiAnabel Pérez-GómezJanina EisenbeisThomas TimmTomohiro IshiiGünter LochnitMarkus BischoffPeter MombaertsTrese Leinders-ZufallFrank ZufallNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Bernd Bufe
Yannick Teuchert
Andreas Schmid
Martina Pyrski
Anabel Pérez-Gómez
Janina Eisenbeis
Thomas Timm
Tomohiro Ishii
Günter Lochnit
Markus Bischoff
Peter Mombaerts
Trese Leinders-Zufall
Frank Zufall
Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour
description The role of chemoreceptors on vomeronasal neurons are not fully understood. Here the authors show that in mice, the vomeronasal chemoreceptor Fpr3 responds to peptides from the bacterial MgrB protein, and that exposure to these peptides drives an avoidance response.
format article
author Bernd Bufe
Yannick Teuchert
Andreas Schmid
Martina Pyrski
Anabel Pérez-Gómez
Janina Eisenbeis
Thomas Timm
Tomohiro Ishii
Günter Lochnit
Markus Bischoff
Peter Mombaerts
Trese Leinders-Zufall
Frank Zufall
author_facet Bernd Bufe
Yannick Teuchert
Andreas Schmid
Martina Pyrski
Anabel Pérez-Gómez
Janina Eisenbeis
Thomas Timm
Tomohiro Ishii
Günter Lochnit
Markus Bischoff
Peter Mombaerts
Trese Leinders-Zufall
Frank Zufall
author_sort Bernd Bufe
title Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour
title_short Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour
title_full Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour
title_fullStr Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour
title_full_unstemmed Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour
title_sort bacterial mgrb peptide activates chemoreceptor fpr3 in mouse accessory olfactory system and drives avoidance behaviour
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/e54176781bf24438a47eaf081f359b20
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