Role of minimally invasive glaucoma surgery in the management of chronic open-angle glaucoma

Abstract To compare the safety and efficacy of phacoemulsification combined with ab-interno trabeculectomy (Trabectome) and phacoemulsification combined with I-Stent inject in patients with medically uncontrolled primary open-angle glaucoma (POAG). A retrospective comparative case series. 70 eyes of...

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Autores principales:	Ojasvi Sharma, Didar Abdulla, Anthony King, Monali Chakrabarti, Tarun Sharma
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/e559e80d85d4435dadb19587bb816d3f
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spelling	oai:doaj.org-article:e559e80d85d4435dadb19587bb816d3f2021-11-08T10:50:59ZRole of minimally invasive glaucoma surgery in the management of chronic open-angle glaucoma10.1038/s41598-021-00808-32045-2322https://doaj.org/article/e559e80d85d4435dadb19587bb816d3f2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-00808-3https://doaj.org/toc/2045-2322Abstract To compare the safety and efficacy of phacoemulsification combined with ab-interno trabeculectomy (Trabectome) and phacoemulsification combined with I-Stent inject in patients with medically uncontrolled primary open-angle glaucoma (POAG). A retrospective comparative case series. 70 eyes of 66 patients completed 2 years follow up after these treatments performed in 2017–2018. 35 eyes of 33 patients underwent combined Phaco-Trabectome (PT); and 35 eyes of 33 patients underwent combined Phaco-I-Stent inject (Pi). Patient demographics and preoperative characteristics are comparable. A 20% drop in IOP was achieved in 27 eyes (77.14%) in PT group and 28 eyes (80%) in Pi group (p = 0.77). Success rate (target IOP achieved and maintained for 2 years) in advance glaucoma was 25% in PT group and 30.7% in Pi group (p = 0.90). In mild to moderate glaucoma, success rate was 85.71% in PT group and 90% in Pi group (p = 0.67). There was no significant difference between two groups with regards to mean reduction in glaucoma medications and complication rates. Trabectome and I-Stent combined with phacoemulsification are equally efficacious and safe for treating patients with medically uncontrolled mild and moderate primary open-angle glaucoma (POAG). However, they are not an effective treatment for patients with advanced glaucoma.Ojasvi SharmaDidar AbdullaAnthony KingMonali ChakrabartiTarun SharmaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ojasvi Sharma Didar Abdulla Anthony King Monali Chakrabarti Tarun Sharma Role of minimally invasive glaucoma surgery in the management of chronic open-angle glaucoma
description	Abstract To compare the safety and efficacy of phacoemulsification combined with ab-interno trabeculectomy (Trabectome) and phacoemulsification combined with I-Stent inject in patients with medically uncontrolled primary open-angle glaucoma (POAG). A retrospective comparative case series. 70 eyes of 66 patients completed 2 years follow up after these treatments performed in 2017–2018. 35 eyes of 33 patients underwent combined Phaco-Trabectome (PT); and 35 eyes of 33 patients underwent combined Phaco-I-Stent inject (Pi). Patient demographics and preoperative characteristics are comparable. A 20% drop in IOP was achieved in 27 eyes (77.14%) in PT group and 28 eyes (80%) in Pi group (p = 0.77). Success rate (target IOP achieved and maintained for 2 years) in advance glaucoma was 25% in PT group and 30.7% in Pi group (p = 0.90). In mild to moderate glaucoma, success rate was 85.71% in PT group and 90% in Pi group (p = 0.67). There was no significant difference between two groups with regards to mean reduction in glaucoma medications and complication rates. Trabectome and I-Stent combined with phacoemulsification are equally efficacious and safe for treating patients with medically uncontrolled mild and moderate primary open-angle glaucoma (POAG). However, they are not an effective treatment for patients with advanced glaucoma.
format	article
author	Ojasvi Sharma Didar Abdulla Anthony King Monali Chakrabarti Tarun Sharma
author_facet	Ojasvi Sharma Didar Abdulla Anthony King Monali Chakrabarti Tarun Sharma
author_sort	Ojasvi Sharma
title	Role of minimally invasive glaucoma surgery in the management of chronic open-angle glaucoma
title_short	Role of minimally invasive glaucoma surgery in the management of chronic open-angle glaucoma
title_full	Role of minimally invasive glaucoma surgery in the management of chronic open-angle glaucoma
title_fullStr	Role of minimally invasive glaucoma surgery in the management of chronic open-angle glaucoma
title_full_unstemmed	Role of minimally invasive glaucoma surgery in the management of chronic open-angle glaucoma
title_sort	role of minimally invasive glaucoma surgery in the management of chronic open-angle glaucoma
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/e559e80d85d4435dadb19587bb816d3f
work_keys_str_mv	AT ojasvisharma roleofminimallyinvasiveglaucomasurgeryinthemanagementofchronicopenangleglaucoma AT didarabdulla roleofminimallyinvasiveglaucomasurgeryinthemanagementofchronicopenangleglaucoma AT anthonyking roleofminimallyinvasiveglaucomasurgeryinthemanagementofchronicopenangleglaucoma AT monalichakrabarti roleofminimallyinvasiveglaucomasurgeryinthemanagementofchronicopenangleglaucoma AT tarunsharma roleofminimallyinvasiveglaucomasurgeryinthemanagementofchronicopenangleglaucoma
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Role of minimally invasive glaucoma surgery in the management of chronic open-angle glaucoma

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