Perivascular cell-specific knockout of the stem cell pluripotency gene Oct4 inhibits angiogenesis
Perivascular cells are essential to the formation and stabilization of new blood vessels during angiogenesis. Here, Hess and Kelly-Goss et al. show that the stem cell pluripotency factor Oct4 promotes perivascular cell survival and migration required for angiogenesis in contexts of tissue injury and...
Guardado en:
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2019
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/e55a3bf1dfe040a6ab7dfaf6ab1c2344 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | Perivascular cells are essential to the formation and stabilization of new blood vessels during angiogenesis. Here, Hess and Kelly-Goss et al. show that the stem cell pluripotency factor Oct4 promotes perivascular cell survival and migration required for angiogenesis in contexts of tissue injury and hypoxia. |
|---|