Metabolism of carbohydrate-containing biopolymers in liver and gastric mucosa of rats with experimental diabetes and varying stress resistance

Aim. To measure concentration of carbohydrate-containing biopolymers in liver and gastric mucosa of rats with alloxan diabetes and varying stressresistance. Materials and methods. The ?open field? test was used to allocate the animals to 2 groups (stress-sensitive and stress-resistant). Insulin-de...

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Autores principales:	Svetlana Vladimirovna Protasova, Evgeny Germanovich Butolin, Artur Valer'evich Oksuzyan
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2010
Materias:	alloxan diabetes glycosaminoglycanes sialoglycoproteins stress-resistant stress-sensitive Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/e55dffff86d34c62b133677cc6043ea4
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spelling	oai:doaj.org-article:e55dffff86d34c62b133677cc6043ea42021-11-14T09:00:14ZMetabolism of carbohydrate-containing biopolymers in liver and gastric mucosa of rats with experimental diabetes and varying stress resistance2072-03512072-037810.14341/2072-0351-6010https://doaj.org/article/e55dffff86d34c62b133677cc6043ea42010-03-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6010https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. To measure concentration of carbohydrate-containing biopolymers in liver and gastric mucosa of rats with alloxan diabetes and varying stressresistance. Materials and methods. The ?open field? test was used to allocate the animals to 2 groups (stress-sensitive and stress-resistant). Insulin-dependentdiabetes was induced by a single s/c injection of alloxan tetrahydrate (170 mg/kg). Total glycosaminoglycanes and gyaluronidase activity were measuredin gastric mucosa. Results. Concentration of glycosaminoglycanes (sialic acids) in the liver increased in animals of both groups and reached a maximum on day 30. Conclusion. Metabolism of sialoglycoproteins in gastric mucosa was dominated by catabolic processes most intense on day 45 after induction of experimentaldiabetesSvetlana Vladimirovna ProtasovaEvgeny Germanovich ButolinArtur Valer'evich OksuzyanEndocrinology Research Centrearticlealloxan diabetesglycosaminoglycanessialoglycoproteinsstress-resistantstress-sensitiveNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 13, Iss 1, Pp 10-12 (2010)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	alloxan diabetes glycosaminoglycanes sialoglycoproteins stress-resistant stress-sensitive Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	alloxan diabetes glycosaminoglycanes sialoglycoproteins stress-resistant stress-sensitive Nutritional diseases. Deficiency diseases RC620-627 Svetlana Vladimirovna Protasova Evgeny Germanovich Butolin Artur Valer'evich Oksuzyan Metabolism of carbohydrate-containing biopolymers in liver and gastric mucosa of rats with experimental diabetes and varying stress resistance
description	Aim. To measure concentration of carbohydrate-containing biopolymers in liver and gastric mucosa of rats with alloxan diabetes and varying stressresistance. Materials and methods. The ?open field? test was used to allocate the animals to 2 groups (stress-sensitive and stress-resistant). Insulin-dependentdiabetes was induced by a single s/c injection of alloxan tetrahydrate (170 mg/kg). Total glycosaminoglycanes and gyaluronidase activity were measuredin gastric mucosa. Results. Concentration of glycosaminoglycanes (sialic acids) in the liver increased in animals of both groups and reached a maximum on day 30. Conclusion. Metabolism of sialoglycoproteins in gastric mucosa was dominated by catabolic processes most intense on day 45 after induction of experimentaldiabetes
format	article
author	Svetlana Vladimirovna Protasova Evgeny Germanovich Butolin Artur Valer'evich Oksuzyan
author_facet	Svetlana Vladimirovna Protasova Evgeny Germanovich Butolin Artur Valer'evich Oksuzyan
author_sort	Svetlana Vladimirovna Protasova
title	Metabolism of carbohydrate-containing biopolymers in liver and gastric mucosa of rats with experimental diabetes and varying stress resistance
title_short	Metabolism of carbohydrate-containing biopolymers in liver and gastric mucosa of rats with experimental diabetes and varying stress resistance
title_full	Metabolism of carbohydrate-containing biopolymers in liver and gastric mucosa of rats with experimental diabetes and varying stress resistance
title_fullStr	Metabolism of carbohydrate-containing biopolymers in liver and gastric mucosa of rats with experimental diabetes and varying stress resistance
title_full_unstemmed	Metabolism of carbohydrate-containing biopolymers in liver and gastric mucosa of rats with experimental diabetes and varying stress resistance
title_sort	metabolism of carbohydrate-containing biopolymers in liver and gastric mucosa of rats with experimental diabetes and varying stress resistance
publisher	Endocrinology Research Centre
publishDate	2010
url	https://doaj.org/article/e55dffff86d34c62b133677cc6043ea4
work_keys_str_mv	AT svetlanavladimirovnaprotasova metabolismofcarbohydratecontainingbiopolymersinliverandgastricmucosaofratswithexperimentaldiabetesandvaryingstressresistance AT evgenygermanovichbutolin metabolismofcarbohydratecontainingbiopolymersinliverandgastricmucosaofratswithexperimentaldiabetesandvaryingstressresistance AT arturvalerevichoksuzyan metabolismofcarbohydratecontainingbiopolymersinliverandgastricmucosaofratswithexperimentaldiabetesandvaryingstressresistance
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Metabolism of carbohydrate-containing biopolymers in liver and gastric mucosa of rats with experimental diabetes and varying stress resistance

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