CLINICAL CHARACTERIZATION OF FUNCTIONAL DISORDERS AFFECTING IMMUNE SYSTEM

Diagnostics of immune functional disorders represents a systemic factor analysis of all disease features, seeking for identification of a primarily affected functional component of the system, its secondary systemic consequences and compensatory rearrangements, aiming for their subsequent correction...

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Autor principal:	A. G. Borisov
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	immune disorders diagnostics. Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/e579da039a924403a1c6c2e778947025
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spelling	oai:doaj.org-article:e579da039a924403a1c6c2e7789470252021-11-18T08:03:37ZCLINICAL CHARACTERIZATION OF FUNCTIONAL DISORDERS AFFECTING IMMUNE SYSTEM1563-06252313-741X10.15789/1563-0625-2013-1-45-50https://doaj.org/article/e579da039a924403a1c6c2e7789470252014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/31https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XDiagnostics of immune functional disorders represents a systemic factor analysis of all disease features, seeking for identification of a primarily affected functional component of the system, its secondary systemic consequences and compensatory rearrangements, aiming for their subsequent correction. However, clinically valid criteria of these disturbances are not yet determined so far.Hence, the aim of our study was to characterize the disorders of immune system functions, as based on clinical data.By virtue of present clinical information, we have revealed that the patients with different diseases, during hospital treatment, exhibit a variety of immunopathological signs that may be classified into different syndromes, i.e., (1) humoral/effector deficiency; (2) macrophage/phagocyte deficiency, and, (3) hyperreactive reaginic syndrome. These disorders are mostly expressed at intermediate-to-severe degree. Upon dissecting mechanisms of their development and levels of immune system dysfunction, a particular group of combined disorders should be specified (resp., mixed and combined pathologies) that need special attention when planning efficient therapeutic programs.A. G. BorisovSPb RAACIarticleimmune disordersdiagnostics.Immunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 15, Iss 1, Pp 45-50 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	immune disorders diagnostics. Immunologic diseases. Allergy RC581-607
spellingShingle	immune disorders diagnostics. Immunologic diseases. Allergy RC581-607 A. G. Borisov CLINICAL CHARACTERIZATION OF FUNCTIONAL DISORDERS AFFECTING IMMUNE SYSTEM
description	Diagnostics of immune functional disorders represents a systemic factor analysis of all disease features, seeking for identification of a primarily affected functional component of the system, its secondary systemic consequences and compensatory rearrangements, aiming for their subsequent correction. However, clinically valid criteria of these disturbances are not yet determined so far.Hence, the aim of our study was to characterize the disorders of immune system functions, as based on clinical data.By virtue of present clinical information, we have revealed that the patients with different diseases, during hospital treatment, exhibit a variety of immunopathological signs that may be classified into different syndromes, i.e., (1) humoral/effector deficiency; (2) macrophage/phagocyte deficiency, and, (3) hyperreactive reaginic syndrome. These disorders are mostly expressed at intermediate-to-severe degree. Upon dissecting mechanisms of their development and levels of immune system dysfunction, a particular group of combined disorders should be specified (resp., mixed and combined pathologies) that need special attention when planning efficient therapeutic programs.
format	article
author	A. G. Borisov
author_facet	A. G. Borisov
author_sort	A. G. Borisov
title	CLINICAL CHARACTERIZATION OF FUNCTIONAL DISORDERS AFFECTING IMMUNE SYSTEM
title_short	CLINICAL CHARACTERIZATION OF FUNCTIONAL DISORDERS AFFECTING IMMUNE SYSTEM
title_full	CLINICAL CHARACTERIZATION OF FUNCTIONAL DISORDERS AFFECTING IMMUNE SYSTEM
title_fullStr	CLINICAL CHARACTERIZATION OF FUNCTIONAL DISORDERS AFFECTING IMMUNE SYSTEM
title_full_unstemmed	CLINICAL CHARACTERIZATION OF FUNCTIONAL DISORDERS AFFECTING IMMUNE SYSTEM
title_sort	clinical characterization of functional disorders affecting immune system
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/e579da039a924403a1c6c2e778947025
work_keys_str_mv	AT agborisov clinicalcharacterizationoffunctionaldisordersaffectingimmunesystem
_version_	1718422576422715392

CLINICAL CHARACTERIZATION OF FUNCTIONAL DISORDERS AFFECTING IMMUNE SYSTEM

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