3D printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration

Muhammad Qasim,1 Farhan Haq,2 Min-Hee Kang,1 Jin-Hoi Kim1 1Department of Stem Cell and Regenerative Biotechnology, Humanized Pig Research Centre (SRC), Konkuk University, Seoul, South Korea; 2Department of Biosciences, Comsats University, Islamabad, Pakistan Abstract: Conventional tissue engineeri...

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Autores principales: Qasim M, Haq F, Kang MH, Kim JH
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Publicado: Dove Medical Press 2019
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spelling oai:doaj.org-article:e57e70fa2046434090ca05a78d7133672021-12-02T07:14:39Z3D printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration1178-2013https://doaj.org/article/e57e70fa2046434090ca05a78d7133672019-02-01T00:00:00Zhttps://www.dovepress.com/3d-printing-approaches-for-cardiac-tissue-engineering-and-role-of-immu-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Muhammad Qasim,1 Farhan Haq,2 Min-Hee Kang,1 Jin-Hoi Kim1 1Department of Stem Cell and Regenerative Biotechnology, Humanized Pig Research Centre (SRC), Konkuk University, Seoul, South Korea; 2Department of Biosciences, Comsats University, Islamabad, Pakistan Abstract: Conventional tissue engineering, cell therapy, and current medical approaches were shown to be successful in reducing mortality rate and complications caused by cardiovascular diseases (CVDs). But still they have many limitations to fully manage CVDs due to complex composition of native myocardium and microvascularization. Fabrication of fully functional construct to replace infarcted area or regeneration of progenitor cells is important to address CVDs burden. Three-dimensional (3D) printed scaffolds and 3D bioprinting technique have potential to develop fully functional heart construct that can integrate with native tissues rapidly. In this review, we presented an overview of 3D printed approaches for cardiac tissue engineering, and advances in 3D bioprinting of cardiac construct and models. We also discussed role of immune modulation to promote tissue regeneration. Keywords: scaffolds, regeneration, cardiovascular diseases, cell therapy  Qasim MHaq FKang MHKim JHDove Medical PressarticleScaffoldsRegenerationCardiovascular diseases (CVDs)Medicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 14, Pp 1311-1333 (2019)
institution DOAJ
collection DOAJ
language EN
topic Scaffolds
Regeneration
Cardiovascular diseases (CVDs)
Medicine (General)
R5-920
spellingShingle Scaffolds
Regeneration
Cardiovascular diseases (CVDs)
Medicine (General)
R5-920
Qasim M
Haq F
Kang MH
Kim JH
3D printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration
description Muhammad Qasim,1 Farhan Haq,2 Min-Hee Kang,1 Jin-Hoi Kim1 1Department of Stem Cell and Regenerative Biotechnology, Humanized Pig Research Centre (SRC), Konkuk University, Seoul, South Korea; 2Department of Biosciences, Comsats University, Islamabad, Pakistan Abstract: Conventional tissue engineering, cell therapy, and current medical approaches were shown to be successful in reducing mortality rate and complications caused by cardiovascular diseases (CVDs). But still they have many limitations to fully manage CVDs due to complex composition of native myocardium and microvascularization. Fabrication of fully functional construct to replace infarcted area or regeneration of progenitor cells is important to address CVDs burden. Three-dimensional (3D) printed scaffolds and 3D bioprinting technique have potential to develop fully functional heart construct that can integrate with native tissues rapidly. In this review, we presented an overview of 3D printed approaches for cardiac tissue engineering, and advances in 3D bioprinting of cardiac construct and models. We also discussed role of immune modulation to promote tissue regeneration. Keywords: scaffolds, regeneration, cardiovascular diseases, cell therapy  
format article
author Qasim M
Haq F
Kang MH
Kim JH
author_facet Qasim M
Haq F
Kang MH
Kim JH
author_sort Qasim M
title 3D printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration
title_short 3D printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration
title_full 3D printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration
title_fullStr 3D printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration
title_full_unstemmed 3D printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration
title_sort 3d printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration
publisher Dove Medical Press
publishDate 2019
url https://doaj.org/article/e57e70fa2046434090ca05a78d713367
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AT haqf 3dprintingapproachesforcardiactissueengineeringandroleofimmunemodulationintissueregeneration
AT kangmh 3dprintingapproachesforcardiactissueengineeringandroleofimmunemodulationintissueregeneration
AT kimjh 3dprintingapproachesforcardiactissueengineeringandroleofimmunemodulationintissueregeneration
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