3D printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration
Muhammad Qasim,1 Farhan Haq,2 Min-Hee Kang,1 Jin-Hoi Kim1 1Department of Stem Cell and Regenerative Biotechnology, Humanized Pig Research Centre (SRC), Konkuk University, Seoul, South Korea; 2Department of Biosciences, Comsats University, Islamabad, Pakistan Abstract: Conventional tissue engineeri...
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Dove Medical Press
2019
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oai:doaj.org-article:e57e70fa2046434090ca05a78d7133672021-12-02T07:14:39Z3D printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration1178-2013https://doaj.org/article/e57e70fa2046434090ca05a78d7133672019-02-01T00:00:00Zhttps://www.dovepress.com/3d-printing-approaches-for-cardiac-tissue-engineering-and-role-of-immu-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Muhammad Qasim,1 Farhan Haq,2 Min-Hee Kang,1 Jin-Hoi Kim1 1Department of Stem Cell and Regenerative Biotechnology, Humanized Pig Research Centre (SRC), Konkuk University, Seoul, South Korea; 2Department of Biosciences, Comsats University, Islamabad, Pakistan Abstract: Conventional tissue engineering, cell therapy, and current medical approaches were shown to be successful in reducing mortality rate and complications caused by cardiovascular diseases (CVDs). But still they have many limitations to fully manage CVDs due to complex composition of native myocardium and microvascularization. Fabrication of fully functional construct to replace infarcted area or regeneration of progenitor cells is important to address CVDs burden. Three-dimensional (3D) printed scaffolds and 3D bioprinting technique have potential to develop fully functional heart construct that can integrate with native tissues rapidly. In this review, we presented an overview of 3D printed approaches for cardiac tissue engineering, and advances in 3D bioprinting of cardiac construct and models. We also discussed role of immune modulation to promote tissue regeneration. Keywords: scaffolds, regeneration, cardiovascular diseases, cell therapy Qasim MHaq FKang MHKim JHDove Medical PressarticleScaffoldsRegenerationCardiovascular diseases (CVDs)Medicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 14, Pp 1311-1333 (2019) |
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Scaffolds Regeneration Cardiovascular diseases (CVDs) Medicine (General) R5-920 |
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Scaffolds Regeneration Cardiovascular diseases (CVDs) Medicine (General) R5-920 Qasim M Haq F Kang MH Kim JH 3D printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration |
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Muhammad Qasim,1 Farhan Haq,2 Min-Hee Kang,1 Jin-Hoi Kim1 1Department of Stem Cell and Regenerative Biotechnology, Humanized Pig Research Centre (SRC), Konkuk University, Seoul, South Korea; 2Department of Biosciences, Comsats University, Islamabad, Pakistan Abstract: Conventional tissue engineering, cell therapy, and current medical approaches were shown to be successful in reducing mortality rate and complications caused by cardiovascular diseases (CVDs). But still they have many limitations to fully manage CVDs due to complex composition of native myocardium and microvascularization. Fabrication of fully functional construct to replace infarcted area or regeneration of progenitor cells is important to address CVDs burden. Three-dimensional (3D) printed scaffolds and 3D bioprinting technique have potential to develop fully functional heart construct that can integrate with native tissues rapidly. In this review, we presented an overview of 3D printed approaches for cardiac tissue engineering, and advances in 3D bioprinting of cardiac construct and models. We also discussed role of immune modulation to promote tissue regeneration. Keywords: scaffolds, regeneration, cardiovascular diseases, cell therapy
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format |
article |
author |
Qasim M Haq F Kang MH Kim JH |
author_facet |
Qasim M Haq F Kang MH Kim JH |
author_sort |
Qasim M |
title |
3D printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration |
title_short |
3D printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration |
title_full |
3D printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration |
title_fullStr |
3D printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration |
title_full_unstemmed |
3D printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration |
title_sort |
3d printing approaches for cardiac tissue engineering and role of immune modulation in tissue regeneration |
publisher |
Dove Medical Press |
publishDate |
2019 |
url |
https://doaj.org/article/e57e70fa2046434090ca05a78d713367 |
work_keys_str_mv |
AT qasimm 3dprintingapproachesforcardiactissueengineeringandroleofimmunemodulationintissueregeneration AT haqf 3dprintingapproachesforcardiactissueengineeringandroleofimmunemodulationintissueregeneration AT kangmh 3dprintingapproachesforcardiactissueengineeringandroleofimmunemodulationintissueregeneration AT kimjh 3dprintingapproachesforcardiactissueengineeringandroleofimmunemodulationintissueregeneration |
_version_ |
1718399551001329664 |