DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production

DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production

Adipose tissue-resident T cells are known to regulate thermogenesis and energy expenditure. Here the authors report that deletion of mitochondria-localized protein DsbA-L in T cells promotes diet-induced thermogenesis via suppressing IFN-γ production.

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Detalles Bibliográficos
Autores principales: Haiyan Zhou, Xinyi Peng, Jie Hu, Liwen Wang, Hairong Luo, Junyan Zhang, Yacheng Zhang, Guobao Li, Yujiao Ji, Jingjing Zhang, Juli Bai, Meilian Liu, Zhiguang Zhou, Feng Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
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Acceso en línea:https://doaj.org/article/e581e3b78d7640c5a2ad5fac0068169b
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Descripción
Sumario:Adipose tissue-resident T cells are known to regulate thermogenesis and energy expenditure. Here the authors report that deletion of mitochondria-localized protein DsbA-L in T cells promotes diet-induced thermogenesis via suppressing IFN-γ production.

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