DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production
Adipose tissue-resident T cells are known to regulate thermogenesis and energy expenditure. Here the authors report that deletion of mitochondria-localized protein DsbA-L in T cells promotes diet-induced thermogenesis via suppressing IFN-γ production.
Guardado en:
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e581e3b78d7640c5a2ad5fac0068169b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:e581e3b78d7640c5a2ad5fac0068169b |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:e581e3b78d7640c5a2ad5fac0068169b2021-12-02T14:12:04ZDsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production10.1038/s41467-020-20665-42041-1723https://doaj.org/article/e581e3b78d7640c5a2ad5fac0068169b2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20665-4https://doaj.org/toc/2041-1723Adipose tissue-resident T cells are known to regulate thermogenesis and energy expenditure. Here the authors report that deletion of mitochondria-localized protein DsbA-L in T cells promotes diet-induced thermogenesis via suppressing IFN-γ production.Haiyan ZhouXinyi PengJie HuLiwen WangHairong LuoJunyan ZhangYacheng ZhangGuobao LiYujiao JiJingjing ZhangJuli BaiMeilian LiuZhiguang ZhouFeng LiuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Haiyan Zhou Xinyi Peng Jie Hu Liwen Wang Hairong Luo Junyan Zhang Yacheng Zhang Guobao Li Yujiao Ji Jingjing Zhang Juli Bai Meilian Liu Zhiguang Zhou Feng Liu DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production |
description |
Adipose tissue-resident T cells are known to regulate thermogenesis and energy expenditure. Here the authors report that deletion of mitochondria-localized protein DsbA-L in T cells promotes diet-induced thermogenesis via suppressing IFN-γ production. |
format |
article |
author |
Haiyan Zhou Xinyi Peng Jie Hu Liwen Wang Hairong Luo Junyan Zhang Yacheng Zhang Guobao Li Yujiao Ji Jingjing Zhang Juli Bai Meilian Liu Zhiguang Zhou Feng Liu |
author_facet |
Haiyan Zhou Xinyi Peng Jie Hu Liwen Wang Hairong Luo Junyan Zhang Yacheng Zhang Guobao Li Yujiao Ji Jingjing Zhang Juli Bai Meilian Liu Zhiguang Zhou Feng Liu |
author_sort |
Haiyan Zhou |
title |
DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production |
title_short |
DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production |
title_full |
DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production |
title_fullStr |
DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production |
title_full_unstemmed |
DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production |
title_sort |
dsba-l deficiency in t cells promotes diet-induced thermogenesis through suppressing ifn-γ production |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/e581e3b78d7640c5a2ad5fac0068169b |
work_keys_str_mv |
AT haiyanzhou dsbaldeficiencyintcellspromotesdietinducedthermogenesisthroughsuppressingifngproduction AT xinyipeng dsbaldeficiencyintcellspromotesdietinducedthermogenesisthroughsuppressingifngproduction AT jiehu dsbaldeficiencyintcellspromotesdietinducedthermogenesisthroughsuppressingifngproduction AT liwenwang dsbaldeficiencyintcellspromotesdietinducedthermogenesisthroughsuppressingifngproduction AT hairongluo dsbaldeficiencyintcellspromotesdietinducedthermogenesisthroughsuppressingifngproduction AT junyanzhang dsbaldeficiencyintcellspromotesdietinducedthermogenesisthroughsuppressingifngproduction AT yachengzhang dsbaldeficiencyintcellspromotesdietinducedthermogenesisthroughsuppressingifngproduction AT guobaoli dsbaldeficiencyintcellspromotesdietinducedthermogenesisthroughsuppressingifngproduction AT yujiaoji dsbaldeficiencyintcellspromotesdietinducedthermogenesisthroughsuppressingifngproduction AT jingjingzhang dsbaldeficiencyintcellspromotesdietinducedthermogenesisthroughsuppressingifngproduction AT julibai dsbaldeficiencyintcellspromotesdietinducedthermogenesisthroughsuppressingifngproduction AT meilianliu dsbaldeficiencyintcellspromotesdietinducedthermogenesisthroughsuppressingifngproduction AT zhiguangzhou dsbaldeficiencyintcellspromotesdietinducedthermogenesisthroughsuppressingifngproduction AT fengliu dsbaldeficiencyintcellspromotesdietinducedthermogenesisthroughsuppressingifngproduction |
_version_ |
1718391876900356096 |