DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production

Adipose tissue-resident T cells are known to regulate thermogenesis and energy expenditure. Here the authors report that deletion of mitochondria-localized protein DsbA-L in T cells promotes diet-induced thermogenesis via suppressing IFN-γ production.

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Autores principales: Haiyan Zhou, Xinyi Peng, Jie Hu, Liwen Wang, Hairong Luo, Junyan Zhang, Yacheng Zhang, Guobao Li, Yujiao Ji, Jingjing Zhang, Juli Bai, Meilian Liu, Zhiguang Zhou, Feng Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e581e3b78d7640c5a2ad5fac0068169b
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spelling oai:doaj.org-article:e581e3b78d7640c5a2ad5fac0068169b2021-12-02T14:12:04ZDsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production10.1038/s41467-020-20665-42041-1723https://doaj.org/article/e581e3b78d7640c5a2ad5fac0068169b2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20665-4https://doaj.org/toc/2041-1723Adipose tissue-resident T cells are known to regulate thermogenesis and energy expenditure. Here the authors report that deletion of mitochondria-localized protein DsbA-L in T cells promotes diet-induced thermogenesis via suppressing IFN-γ production.Haiyan ZhouXinyi PengJie HuLiwen WangHairong LuoJunyan ZhangYacheng ZhangGuobao LiYujiao JiJingjing ZhangJuli BaiMeilian LiuZhiguang ZhouFeng LiuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Haiyan Zhou
Xinyi Peng
Jie Hu
Liwen Wang
Hairong Luo
Junyan Zhang
Yacheng Zhang
Guobao Li
Yujiao Ji
Jingjing Zhang
Juli Bai
Meilian Liu
Zhiguang Zhou
Feng Liu
DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production
description Adipose tissue-resident T cells are known to regulate thermogenesis and energy expenditure. Here the authors report that deletion of mitochondria-localized protein DsbA-L in T cells promotes diet-induced thermogenesis via suppressing IFN-γ production.
format article
author Haiyan Zhou
Xinyi Peng
Jie Hu
Liwen Wang
Hairong Luo
Junyan Zhang
Yacheng Zhang
Guobao Li
Yujiao Ji
Jingjing Zhang
Juli Bai
Meilian Liu
Zhiguang Zhou
Feng Liu
author_facet Haiyan Zhou
Xinyi Peng
Jie Hu
Liwen Wang
Hairong Luo
Junyan Zhang
Yacheng Zhang
Guobao Li
Yujiao Ji
Jingjing Zhang
Juli Bai
Meilian Liu
Zhiguang Zhou
Feng Liu
author_sort Haiyan Zhou
title DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production
title_short DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production
title_full DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production
title_fullStr DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production
title_full_unstemmed DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production
title_sort dsba-l deficiency in t cells promotes diet-induced thermogenesis through suppressing ifn-γ production
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/e581e3b78d7640c5a2ad5fac0068169b
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