A dietary fatty acid counteracts neuronal mechanical sensitization

A dietary fatty acid counteracts neuronal mechanical sensitization

PIEZO2 is a critical component of the mechanism by which innocuous touch causes pain (tactile allodynia). Here, authors find that the dietary fatty acid margaric acid decreases PIEZO2 function in a dose-dependent manner and counteracts neuronal mechanical sensitization by a proalgesic agent.

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Autores principales: Luis O. Romero, Rebeca Caires, Alec R. Nickolls, Alexander T. Chesler, Julio F. Cordero-Morales, Valeria Vásquez
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
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Acceso en línea:https://doaj.org/article/e581e953bfe048c495f317467c7b666c
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