Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women
Abstract The clinical spectrum of hypertensive disorders of pregnancy (HDP) is determined by the interplay between environmental and genetic factors, most of which remains unknown. ERAP1, ERAP2 and LNPEP genes code for multifunctional aminopeptidases involved with antigen processing and degradation...
Guardado en:
Autores principales: | Leonardo Capistrano Ferreira, Carlos Eduardo Maia Gomes, Priya Duggal, Ingrid De Paula Holanda, Amanda Samara de Lima, Paulo Ricardo Porfírio do Nascimento, Selma Maria Bezerra Jeronimo |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e5887c92a4b743b5af54dbf0efbd2baf |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism
por: Zachary Maben, et al.
Publicado: (2021) -
Stapled BIG3 helical peptide ERAP potentiates anti-tumour activity for breast cancer therapeutics
por: Tetsuro Yoshimaru, et al.
Publicado: (2017) -
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP
por: Francesca Bufalieri, et al.
Publicado: (2019) -
The ERAP1 active site cannot productively access the N-terminus of antigenic peptide precursors stably bound onto MHC class I
por: George Mavridis, et al.
Publicado: (2021) -
ERAP1 Controls the Interaction of the Inhibitory Receptor KIR3DL1 With HLA-B51:01 by Affecting Natural Killer Cell Function
por: Silvia D’Amico, et al.
Publicado: (2021)