IMMUNOLOGICAL MECHANISMS OF APOPTOSIS IN PLACENTAL DEVELOPMENT

Abstract. In present review, the data are considered that concern a role of immunological mechanisms controlling the events of apoptosis at different stages of development of placenta. Intensity of apoptotic process in human placenta is progressively increasing in the course of pregnancy, until deli...

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Autor principal:	D. I. Sokolov
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	apoptosis angiogenesis placenta lymphocytes macrophages nkt-cells Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/e592690c01d041ed88d8f6c55159d08d
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spelling	oai:doaj.org-article:e592690c01d041ed88d8f6c55159d08d2021-11-18T08:03:38ZIMMUNOLOGICAL MECHANISMS OF APOPTOSIS IN PLACENTAL DEVELOPMENT1563-06252313-741X10.15789/1563-0625-2008-2-3-125-138https://doaj.org/article/e592690c01d041ed88d8f6c55159d08d2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/110https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. In present review, the data are considered that concern a role of immunological mechanisms controlling the events of apoptosis at different stages of development of placenta. Intensity of apoptotic process in human placenta is progressively increasing in the course of pregnancy, until delivery act. The processes of apoptosis induction and its prevention in placental cells are inseparably linked to development of placenta and formation of vascular system, as controlled by trophoblast cells, as well as by maternal fetal immune cells. T-lymphocytes, natural killer cells, NKT-cells and macrophages that perform surveillance over the processes of angiogenesis and apoptosis in placental tissue, thus providing its normal development and functioning.D. I. SokolovSPb RAACIarticleapoptosisangiogenesisplacentalymphocytesmacrophagesnkt-cellsImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 10, Iss 2-3, Pp 125-138 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	apoptosis angiogenesis placenta lymphocytes macrophages nkt-cells Immunologic diseases. Allergy RC581-607
spellingShingle	apoptosis angiogenesis placenta lymphocytes macrophages nkt-cells Immunologic diseases. Allergy RC581-607 D. I. Sokolov IMMUNOLOGICAL MECHANISMS OF APOPTOSIS IN PLACENTAL DEVELOPMENT
description	Abstract. In present review, the data are considered that concern a role of immunological mechanisms controlling the events of apoptosis at different stages of development of placenta. Intensity of apoptotic process in human placenta is progressively increasing in the course of pregnancy, until delivery act. The processes of apoptosis induction and its prevention in placental cells are inseparably linked to development of placenta and formation of vascular system, as controlled by trophoblast cells, as well as by maternal fetal immune cells. T-lymphocytes, natural killer cells, NKT-cells and macrophages that perform surveillance over the processes of angiogenesis and apoptosis in placental tissue, thus providing its normal development and functioning.
format	article
author	D. I. Sokolov
author_facet	D. I. Sokolov
author_sort	D. I. Sokolov
title	IMMUNOLOGICAL MECHANISMS OF APOPTOSIS IN PLACENTAL DEVELOPMENT
title_short	IMMUNOLOGICAL MECHANISMS OF APOPTOSIS IN PLACENTAL DEVELOPMENT
title_full	IMMUNOLOGICAL MECHANISMS OF APOPTOSIS IN PLACENTAL DEVELOPMENT
title_fullStr	IMMUNOLOGICAL MECHANISMS OF APOPTOSIS IN PLACENTAL DEVELOPMENT
title_full_unstemmed	IMMUNOLOGICAL MECHANISMS OF APOPTOSIS IN PLACENTAL DEVELOPMENT
title_sort	immunological mechanisms of apoptosis in placental development
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/e592690c01d041ed88d8f6c55159d08d
work_keys_str_mv	AT disokolov immunologicalmechanismsofapoptosisinplacentaldevelopment
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IMMUNOLOGICAL MECHANISMS OF APOPTOSIS IN PLACENTAL DEVELOPMENT

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