Mitofusin-2 stabilizes adherens junctions and suppresses endothelial inflammation via modulation of β-catenin signaling
Endothelial tissues must have intact barrier function, but this may be disrupted during inflammation. Here, the authors show that the mitochondrial protein Mitofusin-2 stabilizes cell–cell adherens junctions in endothelial cells during homeostasis and binds the transcriptional activator β-catenin up...
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Autores principales: | Young-Mee Kim, Sarah Krantz, Ankit Jambusaria, Peter T. Toth, Hyung-Geun Moon, Isuru Gunarathna, Gye Young Park, Jalees Rehman |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/e5953cf98299418595f144ad5dbc7489 |
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