A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset

A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset

Antibiotic resistance is a major threat across the whole healthcare spectrum. Here, the authors report on the development of biodegradable guanidinium functionalized polycarbonates and demonstrate antimicrobial activity against drug resistant infections.

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Autores principales: Willy Chin, Guansheng Zhong, Qinqin Pu, Chuan Yang, Weiyang Lou, Paola Florez De Sessions, Balamurugan Periaswamy, Ashlynn Lee, Zhen Chang Liang, Xin Ding, Shujun Gao, Collins Wenhan Chu, Simone Bianco, Chang Bao, Yen Wah Tong, Weimin Fan, Min Wu, James L. Hedrick, Yi Yan Yang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
Q
Acceso en línea:https://doaj.org/article/e5987885c4ec47ccbe0cf7142ecdd956
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spelling oai:doaj.org-article:e5987885c4ec47ccbe0cf7142ecdd9562021-12-02T14:39:23ZA macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset10.1038/s41467-018-03325-62041-1723https://doaj.org/article/e5987885c4ec47ccbe0cf7142ecdd9562018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03325-6https://doaj.org/toc/2041-1723Antibiotic resistance is a major threat across the whole healthcare spectrum. Here, the authors report on the development of biodegradable guanidinium functionalized polycarbonates and demonstrate antimicrobial activity against drug resistant infections.Willy ChinGuansheng ZhongQinqin PuChuan YangWeiyang LouPaola Florez De SessionsBalamurugan PeriaswamyAshlynn LeeZhen Chang LiangXin DingShujun GaoCollins Wenhan ChuSimone BiancoChang BaoYen Wah TongWeimin FanMin WuJames L. HedrickYi Yan YangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Willy Chin
Guansheng Zhong
Qinqin Pu
Chuan Yang
Weiyang Lou
Paola Florez De Sessions
Balamurugan Periaswamy
Ashlynn Lee
Zhen Chang Liang
Xin Ding
Shujun Gao
Collins Wenhan Chu
Simone Bianco
Chang Bao
Yen Wah Tong
Weimin Fan
Min Wu
James L. Hedrick
Yi Yan Yang
A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset
description Antibiotic resistance is a major threat across the whole healthcare spectrum. Here, the authors report on the development of biodegradable guanidinium functionalized polycarbonates and demonstrate antimicrobial activity against drug resistant infections.
format article
author Willy Chin
Guansheng Zhong
Qinqin Pu
Chuan Yang
Weiyang Lou
Paola Florez De Sessions
Balamurugan Periaswamy
Ashlynn Lee
Zhen Chang Liang
Xin Ding
Shujun Gao
Collins Wenhan Chu
Simone Bianco
Chang Bao
Yen Wah Tong
Weimin Fan
Min Wu
James L. Hedrick
Yi Yan Yang
author_facet Willy Chin
Guansheng Zhong
Qinqin Pu
Chuan Yang
Weiyang Lou
Paola Florez De Sessions
Balamurugan Periaswamy
Ashlynn Lee
Zhen Chang Liang
Xin Ding
Shujun Gao
Collins Wenhan Chu
Simone Bianco
Chang Bao
Yen Wah Tong
Weimin Fan
Min Wu
James L. Hedrick
Yi Yan Yang
author_sort Willy Chin
title A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset
title_short A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset
title_full A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset
title_fullStr A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset
title_full_unstemmed A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset
title_sort macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/e5987885c4ec47ccbe0cf7142ecdd956
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