Functional exploration of colorectal cancer genomes using Drosophila

Colorectal cancers carry multiple mutations. Here, the authors use Drosophilaas a model organism and assess multiple combinations of mutations and their response to various drugs, providing further insight into drug resistance mechanisms.

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Detalles Bibliográficos
Autores principales: Erdem Bangi, Claudio Murgia, Alexander G.S. Teague, Owen J. Sansom, Ross L. Cagan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/e59e5a0467fd4abfb5f65e06e4a7d710
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Descripción
Sumario:Colorectal cancers carry multiple mutations. Here, the authors use Drosophilaas a model organism and assess multiple combinations of mutations and their response to various drugs, providing further insight into drug resistance mechanisms.