Functional exploration of colorectal cancer genomes using Drosophila

Colorectal cancers carry multiple mutations. Here, the authors use Drosophilaas a model organism and assess multiple combinations of mutations and their response to various drugs, providing further insight into drug resistance mechanisms.

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Autores principales: Erdem Bangi, Claudio Murgia, Alexander G.S. Teague, Owen J. Sansom, Ross L. Cagan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/e59e5a0467fd4abfb5f65e06e4a7d710
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spelling oai:doaj.org-article:e59e5a0467fd4abfb5f65e06e4a7d7102021-12-02T15:34:50ZFunctional exploration of colorectal cancer genomes using Drosophila10.1038/ncomms136152041-1723https://doaj.org/article/e59e5a0467fd4abfb5f65e06e4a7d7102016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13615https://doaj.org/toc/2041-1723Colorectal cancers carry multiple mutations. Here, the authors use Drosophilaas a model organism and assess multiple combinations of mutations and their response to various drugs, providing further insight into drug resistance mechanisms.Erdem BangiClaudio MurgiaAlexander G.S. TeagueOwen J. SansomRoss L. CaganNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Erdem Bangi
Claudio Murgia
Alexander G.S. Teague
Owen J. Sansom
Ross L. Cagan
Functional exploration of colorectal cancer genomes using Drosophila
description Colorectal cancers carry multiple mutations. Here, the authors use Drosophilaas a model organism and assess multiple combinations of mutations and their response to various drugs, providing further insight into drug resistance mechanisms.
format article
author Erdem Bangi
Claudio Murgia
Alexander G.S. Teague
Owen J. Sansom
Ross L. Cagan
author_facet Erdem Bangi
Claudio Murgia
Alexander G.S. Teague
Owen J. Sansom
Ross L. Cagan
author_sort Erdem Bangi
title Functional exploration of colorectal cancer genomes using Drosophila
title_short Functional exploration of colorectal cancer genomes using Drosophila
title_full Functional exploration of colorectal cancer genomes using Drosophila
title_fullStr Functional exploration of colorectal cancer genomes using Drosophila
title_full_unstemmed Functional exploration of colorectal cancer genomes using Drosophila
title_sort functional exploration of colorectal cancer genomes using drosophila
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/e59e5a0467fd4abfb5f65e06e4a7d710
work_keys_str_mv AT erdembangi functionalexplorationofcolorectalcancergenomesusingdrosophila
AT claudiomurgia functionalexplorationofcolorectalcancergenomesusingdrosophila
AT alexandergsteague functionalexplorationofcolorectalcancergenomesusingdrosophila
AT owenjsansom functionalexplorationofcolorectalcancergenomesusingdrosophila
AT rosslcagan functionalexplorationofcolorectalcancergenomesusingdrosophila
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