Functional exploration of colorectal cancer genomes using Drosophila

Colorectal cancers carry multiple mutations. Here, the authors use Drosophilaas a model organism and assess multiple combinations of mutations and their response to various drugs, providing further insight into drug resistance mechanisms.

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Auteurs principaux:	Erdem Bangi, Claudio Murgia, Alexander G.S. Teague, Owen J. Sansom, Ross L. Cagan
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2016
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/e59e5a0467fd4abfb5f65e06e4a7d710
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id	oai:doaj.org-article:e59e5a0467fd4abfb5f65e06e4a7d710
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spelling	oai:doaj.org-article:e59e5a0467fd4abfb5f65e06e4a7d7102021-12-02T15:34:50ZFunctional exploration of colorectal cancer genomes using Drosophila10.1038/ncomms136152041-1723https://doaj.org/article/e59e5a0467fd4abfb5f65e06e4a7d7102016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13615https://doaj.org/toc/2041-1723Colorectal cancers carry multiple mutations. Here, the authors use Drosophilaas a model organism and assess multiple combinations of mutations and their response to various drugs, providing further insight into drug resistance mechanisms.Erdem BangiClaudio MurgiaAlexander G.S. TeagueOwen J. SansomRoss L. CaganNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Erdem Bangi Claudio Murgia Alexander G.S. Teague Owen J. Sansom Ross L. Cagan Functional exploration of colorectal cancer genomes using Drosophila
description	Colorectal cancers carry multiple mutations. Here, the authors use Drosophilaas a model organism and assess multiple combinations of mutations and their response to various drugs, providing further insight into drug resistance mechanisms.
format	article
author	Erdem Bangi Claudio Murgia Alexander G.S. Teague Owen J. Sansom Ross L. Cagan
author_facet	Erdem Bangi Claudio Murgia Alexander G.S. Teague Owen J. Sansom Ross L. Cagan
author_sort	Erdem Bangi
title	Functional exploration of colorectal cancer genomes using Drosophila
title_short	Functional exploration of colorectal cancer genomes using Drosophila
title_full	Functional exploration of colorectal cancer genomes using Drosophila
title_fullStr	Functional exploration of colorectal cancer genomes using Drosophila
title_full_unstemmed	Functional exploration of colorectal cancer genomes using Drosophila
title_sort	functional exploration of colorectal cancer genomes using drosophila
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/e59e5a0467fd4abfb5f65e06e4a7d710
work_keys_str_mv	AT erdembangi functionalexplorationofcolorectalcancergenomesusingdrosophila AT claudiomurgia functionalexplorationofcolorectalcancergenomesusingdrosophila AT alexandergsteague functionalexplorationofcolorectalcancergenomesusingdrosophila AT owenjsansom functionalexplorationofcolorectalcancergenomesusingdrosophila AT rosslcagan functionalexplorationofcolorectalcancergenomesusingdrosophila
_version_	1718386751907561472

Functional exploration of colorectal cancer genomes using Drosophila

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