Functional exploration of colorectal cancer genomes using Drosophila
Colorectal cancers carry multiple mutations. Here, the authors use Drosophilaas a model organism and assess multiple combinations of mutations and their response to various drugs, providing further insight into drug resistance mechanisms.
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Nature Portfolio
2016
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oai:doaj.org-article:e59e5a0467fd4abfb5f65e06e4a7d7102021-12-02T15:34:50ZFunctional exploration of colorectal cancer genomes using Drosophila10.1038/ncomms136152041-1723https://doaj.org/article/e59e5a0467fd4abfb5f65e06e4a7d7102016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13615https://doaj.org/toc/2041-1723Colorectal cancers carry multiple mutations. Here, the authors use Drosophilaas a model organism and assess multiple combinations of mutations and their response to various drugs, providing further insight into drug resistance mechanisms.Erdem BangiClaudio MurgiaAlexander G.S. TeagueOwen J. SansomRoss L. CaganNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016) |
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EN |
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Science Q |
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Science Q Erdem Bangi Claudio Murgia Alexander G.S. Teague Owen J. Sansom Ross L. Cagan Functional exploration of colorectal cancer genomes using Drosophila |
description |
Colorectal cancers carry multiple mutations. Here, the authors use Drosophilaas a model organism and assess multiple combinations of mutations and their response to various drugs, providing further insight into drug resistance mechanisms. |
format |
article |
author |
Erdem Bangi Claudio Murgia Alexander G.S. Teague Owen J. Sansom Ross L. Cagan |
author_facet |
Erdem Bangi Claudio Murgia Alexander G.S. Teague Owen J. Sansom Ross L. Cagan |
author_sort |
Erdem Bangi |
title |
Functional exploration of colorectal cancer genomes using Drosophila |
title_short |
Functional exploration of colorectal cancer genomes using Drosophila |
title_full |
Functional exploration of colorectal cancer genomes using Drosophila |
title_fullStr |
Functional exploration of colorectal cancer genomes using Drosophila |
title_full_unstemmed |
Functional exploration of colorectal cancer genomes using Drosophila |
title_sort |
functional exploration of colorectal cancer genomes using drosophila |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/e59e5a0467fd4abfb5f65e06e4a7d710 |
work_keys_str_mv |
AT erdembangi functionalexplorationofcolorectalcancergenomesusingdrosophila AT claudiomurgia functionalexplorationofcolorectalcancergenomesusingdrosophila AT alexandergsteague functionalexplorationofcolorectalcancergenomesusingdrosophila AT owenjsansom functionalexplorationofcolorectalcancergenomesusingdrosophila AT rosslcagan functionalexplorationofcolorectalcancergenomesusingdrosophila |
_version_ |
1718386751907561472 |