Laparoscopic and hand-assisted laparoscopic donor nephrectomy: A systematic review and meta-analysis

Objective: To compare the perioperative outcomes of hand-assisted laparoscopic donor nephrectomy (HALDN) and pure LDN, as HALDN and LDN are the two most widely used techniques of DN to treat end-stage renal disease. Methods: In this systematic review and meta-analysis, we performed a literature sear...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mark P. Broe, Rose Galvin, Lorna G. Keenan, Richard E. Power
Formato:	article
Lenguaje:	EN
Publicado:	Taylor & Francis Group 2018
Materias:	Diseases of the genitourinary system. Urology RC870-923
Acceso en línea:	https://doaj.org/article/e5a5f01839b648298ed636093bd6ab80
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e5a5f01839b648298ed636093bd6ab80
record_format	dspace
spelling	oai:doaj.org-article:e5a5f01839b648298ed636093bd6ab802021-12-02T08:22:58ZLaparoscopic and hand-assisted laparoscopic donor nephrectomy: A systematic review and meta-analysis2090-598X10.1016/j.aju.2018.02.003https://doaj.org/article/e5a5f01839b648298ed636093bd6ab802018-09-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2090598X18300366https://doaj.org/toc/2090-598XObjective: To compare the perioperative outcomes of hand-assisted laparoscopic donor nephrectomy (HALDN) and pure LDN, as HALDN and LDN are the two most widely used techniques of DN to treat end-stage renal disease. Methods: In this systematic review and meta-analysis, we performed a literature search of PubMed, Embase, Web of Science, and Cochrane from 01/01/1995 to 31/12/2014. The primary outcome was conversion to an open procedure. Secondary outcomes were warm ischaemia time (WIT), operation time (OT), estimated blood loss (EBL), complications, and length of stay (LOS). Data analysed were presented as odds ratios (ORs) or weighted mean differences (WMDs) with 95% confidence intervals (CIs), I2, and P values. Subgroup analysis was performed. Results: There were 24 studies included in the meta-analysis; three randomised controlled trials (RCTs), one randomised pilot study, two prospective, and 18 retrospective cohort studies. There were no differences in conversion to an open procedure between the two techniques for both RCTs (OR 0.42, 95% CI 0.06, 2.90; I2 = 0%, P < 0.001) and cohort studies (OR 1.06, 95% CI 0.63, 1.78; I2 = 0%, P = 0.84). WIT was shorter for the HALDN (−41.79 s, 95% CI −71.85, −11.74; I2 = 96%, P = 0.006), as was the OT (−26.32 min, 95% CI −40.67, −11.97; I2 = 95%, P < 0.001). There was no statistically significant difference in EBL, complications or LOS. Conclusion: There is little statistical evidence to recommend one technique. HALDN is associated with a shorter WIT and OT. LDN has equal safety to HALDN. Further studies are required. Keywords: Laparoscopic donor nephrectomy, Hand-assisted donor nephrectomy, Renal transplantationMark P. BroeRose GalvinLorna G. KeenanRichard E. PowerTaylor & Francis GrouparticleDiseases of the genitourinary system. UrologyRC870-923ENArab Journal of Urology, Vol 16, Iss 3, Pp 322-334 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the genitourinary system. Urology RC870-923
spellingShingle	Diseases of the genitourinary system. Urology RC870-923 Mark P. Broe Rose Galvin Lorna G. Keenan Richard E. Power Laparoscopic and hand-assisted laparoscopic donor nephrectomy: A systematic review and meta-analysis
description	Objective: To compare the perioperative outcomes of hand-assisted laparoscopic donor nephrectomy (HALDN) and pure LDN, as HALDN and LDN are the two most widely used techniques of DN to treat end-stage renal disease. Methods: In this systematic review and meta-analysis, we performed a literature search of PubMed, Embase, Web of Science, and Cochrane from 01/01/1995 to 31/12/2014. The primary outcome was conversion to an open procedure. Secondary outcomes were warm ischaemia time (WIT), operation time (OT), estimated blood loss (EBL), complications, and length of stay (LOS). Data analysed were presented as odds ratios (ORs) or weighted mean differences (WMDs) with 95% confidence intervals (CIs), I2, and P values. Subgroup analysis was performed. Results: There were 24 studies included in the meta-analysis; three randomised controlled trials (RCTs), one randomised pilot study, two prospective, and 18 retrospective cohort studies. There were no differences in conversion to an open procedure between the two techniques for both RCTs (OR 0.42, 95% CI 0.06, 2.90; I2 = 0%, P < 0.001) and cohort studies (OR 1.06, 95% CI 0.63, 1.78; I2 = 0%, P = 0.84). WIT was shorter for the HALDN (−41.79 s, 95% CI −71.85, −11.74; I2 = 96%, P = 0.006), as was the OT (−26.32 min, 95% CI −40.67, −11.97; I2 = 95%, P < 0.001). There was no statistically significant difference in EBL, complications or LOS. Conclusion: There is little statistical evidence to recommend one technique. HALDN is associated with a shorter WIT and OT. LDN has equal safety to HALDN. Further studies are required. Keywords: Laparoscopic donor nephrectomy, Hand-assisted donor nephrectomy, Renal transplantation
format	article
author	Mark P. Broe Rose Galvin Lorna G. Keenan Richard E. Power
author_facet	Mark P. Broe Rose Galvin Lorna G. Keenan Richard E. Power
author_sort	Mark P. Broe
title	Laparoscopic and hand-assisted laparoscopic donor nephrectomy: A systematic review and meta-analysis
title_short	Laparoscopic and hand-assisted laparoscopic donor nephrectomy: A systematic review and meta-analysis
title_full	Laparoscopic and hand-assisted laparoscopic donor nephrectomy: A systematic review and meta-analysis
title_fullStr	Laparoscopic and hand-assisted laparoscopic donor nephrectomy: A systematic review and meta-analysis
title_full_unstemmed	Laparoscopic and hand-assisted laparoscopic donor nephrectomy: A systematic review and meta-analysis
title_sort	laparoscopic and hand-assisted laparoscopic donor nephrectomy: a systematic review and meta-analysis
publisher	Taylor & Francis Group
publishDate	2018
url	https://doaj.org/article/e5a5f01839b648298ed636093bd6ab80
work_keys_str_mv	AT markpbroe laparoscopicandhandassistedlaparoscopicdonornephrectomyasystematicreviewandmetaanalysis AT rosegalvin laparoscopicandhandassistedlaparoscopicdonornephrectomyasystematicreviewandmetaanalysis AT lornagkeenan laparoscopicandhandassistedlaparoscopicdonornephrectomyasystematicreviewandmetaanalysis AT richardepower laparoscopicandhandassistedlaparoscopicdonornephrectomyasystematicreviewandmetaanalysis
_version_	1718398576357277696

Laparoscopic and hand-assisted laparoscopic donor nephrectomy: A systematic review and meta-analysis

Ejemplares similares