Genetic variation at the CD28 locus and its impact on expansion of pro-inflammatory CD28 negative T cells in healthy individuals

Genetic variation at the CD28 locus and its impact on expansion of pro-inflammatory CD28 negative T cells in healthy individuals

Abstract The CD28 locus is associated with susceptibility to a variety of autoimmune and immune-mediated inflammatory diseases including primary sclerosing cholangitis (PSC). Previously, we linked the CD28 pathway in PSC disease pathology and found that vitamin D could maintain CD28 expression. Here...

Full description

Saved in:
Bibliographic Details
Main Authors: Evaggelia Liaskou, Louisa Jeffery, Dimitrios Chanouzas, Blagoje Soskic, Michael F. Seldin, Lorraine Harper, David Sansom, Gideon M. Hirschfield
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/e5a9b051286947d2a6faeaf9453b110f
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/e5a9b051286947d2a6faeaf9453b110f

Similar Items