Structural basis for Ca2+-dependent activation of a plant metacaspase

Structural basis for Ca2+-dependent activation of a plant metacaspase

Plant metacaspases mediate immune response following activation by Ca2+. Here, via crystallography and functional analyses, the authors show that a linker domain in Arabidopsis Metacaspase 4 blocks substrate access to the active site but is cleaved multiple times in the presence of Ca2+ to allow enz...

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Autores principales: Ping Zhu, Xiao-Hong Yu, Cheng Wang, Qingfang Zhang, Wu Liu, Sean McSweeney, John Shanklin, Eric Lam, Qun Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/e5aae62ead4748e8a9ae606526a29d0f
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