Phosphorylation of the proline-rich domain of WAVE3 drives its oncogenic activity in breast cancer

Abstract Post-translational modification of proteins, such as tyrosine phosphorylation, plays a major role in driving the oncogenic activity of oncogenes. WAVE3 (WASF3), an adaptor and actin cytoskeleton remodeling protein, contributes to cell migration, cancer cell invasion, and metastasis. WAVE3 p...

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Autores principales: Urna Kansakar, Wei Wang, Vesna Markovic, Khalid Sossey-Alaoui
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e5b4649c0c4d4b358bb58b34cc1b4a06
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