Helicase promotes replication re-initiation from an RNA transcript

During DNA replication, replicative helicases play an essential role for DNA unwinding to occur. Here the authors find that bacteriophage T7 helicase is also involved in replication re-initiation by interacting with a non-replicating DNAP and increasing unwinding rate.

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Bibliographic Details
Main Authors:	Bo Sun, Anupam Singh, Shemaila Sultana, James T. Inman, Smita S. Patel, Michelle D. Wang
Format:	article
Language:	EN
Published:	Nature Portfolio 2018
Subjects:	Science Q
Online Access:	https://doaj.org/article/e5b4ac43bbc64c9a8f15790539abd4e6
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spelling	oai:doaj.org-article:e5b4ac43bbc64c9a8f15790539abd4e62021-12-02T17:31:43ZHelicase promotes replication re-initiation from an RNA transcript10.1038/s41467-018-04702-x2041-1723https://doaj.org/article/e5b4ac43bbc64c9a8f15790539abd4e62018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04702-xhttps://doaj.org/toc/2041-1723During DNA replication, replicative helicases play an essential role for DNA unwinding to occur. Here the authors find that bacteriophage T7 helicase is also involved in replication re-initiation by interacting with a non-replicating DNAP and increasing unwinding rate.Bo SunAnupam SinghShemaila SultanaJames T. InmanSmita S. PatelMichelle D. WangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Bo Sun Anupam Singh Shemaila Sultana James T. Inman Smita S. Patel Michelle D. Wang Helicase promotes replication re-initiation from an RNA transcript
description	During DNA replication, replicative helicases play an essential role for DNA unwinding to occur. Here the authors find that bacteriophage T7 helicase is also involved in replication re-initiation by interacting with a non-replicating DNAP and increasing unwinding rate.
format	article
author	Bo Sun Anupam Singh Shemaila Sultana James T. Inman Smita S. Patel Michelle D. Wang
author_facet	Bo Sun Anupam Singh Shemaila Sultana James T. Inman Smita S. Patel Michelle D. Wang
author_sort	Bo Sun
title	Helicase promotes replication re-initiation from an RNA transcript
title_short	Helicase promotes replication re-initiation from an RNA transcript
title_full	Helicase promotes replication re-initiation from an RNA transcript
title_fullStr	Helicase promotes replication re-initiation from an RNA transcript
title_full_unstemmed	Helicase promotes replication re-initiation from an RNA transcript
title_sort	helicase promotes replication re-initiation from an rna transcript
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/e5b4ac43bbc64c9a8f15790539abd4e6
work_keys_str_mv	AT bosun helicasepromotesreplicationreinitiationfromanrnatranscript AT anupamsingh helicasepromotesreplicationreinitiationfromanrnatranscript AT shemailasultana helicasepromotesreplicationreinitiationfromanrnatranscript AT jamestinman helicasepromotesreplicationreinitiationfromanrnatranscript AT smitaspatel helicasepromotesreplicationreinitiationfromanrnatranscript AT michelledwang helicasepromotesreplicationreinitiationfromanrnatranscript
_version_	1718380527005728768

Helicase promotes replication re-initiation from an RNA transcript

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