Real-time 3D single molecule tracking

Single molecule observation has been limited to tethered molecules to ensure that the target remains in the field of view (FOV). Here, the authors develop a real-time tracking method that locks onto rapidly diffusing targets and tracks them in a 3D volume, enabling single molecules to remain in the...

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Autores principales: Shangguo Hou, Jack Exell, Kevin Welsher
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/e5b9c20cbff141eab604d5fdecdb9b17
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spelling oai:doaj.org-article:e5b9c20cbff141eab604d5fdecdb9b172021-12-02T15:33:17ZReal-time 3D single molecule tracking10.1038/s41467-020-17444-62041-1723https://doaj.org/article/e5b9c20cbff141eab604d5fdecdb9b172020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17444-6https://doaj.org/toc/2041-1723Single molecule observation has been limited to tethered molecules to ensure that the target remains in the field of view (FOV). Here, the authors develop a real-time tracking method that locks onto rapidly diffusing targets and tracks them in a 3D volume, enabling single molecules to remain in the FOV for minutes at a time.Shangguo HouJack ExellKevin WelsherNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shangguo Hou
Jack Exell
Kevin Welsher
Real-time 3D single molecule tracking
description Single molecule observation has been limited to tethered molecules to ensure that the target remains in the field of view (FOV). Here, the authors develop a real-time tracking method that locks onto rapidly diffusing targets and tracks them in a 3D volume, enabling single molecules to remain in the FOV for minutes at a time.
format article
author Shangguo Hou
Jack Exell
Kevin Welsher
author_facet Shangguo Hou
Jack Exell
Kevin Welsher
author_sort Shangguo Hou
title Real-time 3D single molecule tracking
title_short Real-time 3D single molecule tracking
title_full Real-time 3D single molecule tracking
title_fullStr Real-time 3D single molecule tracking
title_full_unstemmed Real-time 3D single molecule tracking
title_sort real-time 3d single molecule tracking
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/e5b9c20cbff141eab604d5fdecdb9b17
work_keys_str_mv AT shangguohou realtime3dsinglemoleculetracking
AT jackexell realtime3dsinglemoleculetracking
AT kevinwelsher realtime3dsinglemoleculetracking
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