Differential methylation is associated with non-syndromic cleft lip and palate and contributes to penetrance effects

Abstract Non-syndromic cleft lip and/or palate (NSCLP) is a common congenital malformation with a multifactorial model of inheritance. Although several at-risk alleles have been identified, they do not completely explain the high heritability. We postulate that epigenetic factors as DNA methylation...

Full description

Saved in:
Bibliographic Details
Main Authors: Lucas Alvizi, Xiayi Ke, Luciano Abreu Brito, Rimante Seselgyte, Gudrun E. Moore, Philip Stanier, Maria Rita Passos-Bueno
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/e5bb70625e764a11be2c07ab251f41fb
Tags: Add Tag
No Tags, Be the first to tag this record!