Data integration workflow for search of disease driving genes and genetic variants.

Comprehensive characterization of a gene's impact on phenotypes requires knowledge of the context of the gene. To address this issue we introduce a systematic data integration method Candidate Genes and SNPs (CANGES) that links SNP and linkage disequilibrium data to pathway- and protein-protein...

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Bibliographic Details
Main Authors: Sirkku Karinen, Tuomas Heikkinen, Heli Nevanlinna, Sampsa Hautaniemi
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
R
Q
Online Access:https://doaj.org/article/e5bdbf09ac664c2eb2a02c516c9a3014
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