A multi-sample approach increases the accuracy of transcript assembly

Transcript assembly is an important step in analysis of RNA-seq data whose accuracy influences downstream quantification, detection and characterization of alternative splice variants. Here, the authors develop PsiCLASS, a transcript assembler leveraging simultaneous analysis of multiple RNA-seq sam...

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Autores principales: Li Song, Sarven Sabunciyan, Guangyu Yang, Liliana Florea
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/e5c2fe458e40423f92d2ea2ad8d1931e
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Sumario:Transcript assembly is an important step in analysis of RNA-seq data whose accuracy influences downstream quantification, detection and characterization of alternative splice variants. Here, the authors develop PsiCLASS, a transcript assembler leveraging simultaneous analysis of multiple RNA-seq samples.