Mortality trends in an ambulatory multidisciplinary heart failure unit from 2001 to 2018

Abstract To assess mortality trends at 1 and 3 years from 2001 to 2018 in a real-life cohort of HF outpatients from different etiologies with depressed and preserved LVEF. A total of 2368 consecutive patients with HF (mean age 66.4 ± 12.9 years, 71% men, 15.4% with preserved LVEF) admitted to a HF c...

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Autores principales:	Giosafat Spitaleri, Josep Lupón, Mar Domingo, Evelyn Santiago-Vacas, Pau Codina, Elisabet Zamora, Germán Cediel, Javier Santesmases, Crisanto Diez-Quevedo, Maria Isabel Troya, Maria Boldo, Salvador Altmir, Nuria Alonso, Beatriz González, Julio Núñez, Antoni Bayes-Genis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/e5c30ec096344f0da1e3b50ea1f295d2
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spelling	oai:doaj.org-article:e5c30ec096344f0da1e3b50ea1f295d22021-12-02T14:12:41ZMortality trends in an ambulatory multidisciplinary heart failure unit from 2001 to 201810.1038/s41598-020-79926-32045-2322https://doaj.org/article/e5c30ec096344f0da1e3b50ea1f295d22021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-79926-3https://doaj.org/toc/2045-2322Abstract To assess mortality trends at 1 and 3 years from 2001 to 2018 in a real-life cohort of HF outpatients from different etiologies with depressed and preserved LVEF. A total of 2368 consecutive patients with HF (mean age 66.4 ± 12.9 years, 71% men, 15.4% with preserved LVEF) admitted to a HF clinic from August 2001 to September 2018 were included in the study. Patients were divided into five quintiles (Q) according to the period of admission. Trends for all-cause and cardiovascular mortality from Q1 to Q5 were assessed by linear regression. Patients with LVEF < 50% had a progressive decrease in the rates of all-cause and cardiovascular death at 1 year (12.1% in Q1 to 6.5% in Q5, p = 0.003; and 8.4% in Q1 to 3.8% in Q5, p = 0.007, respectively) and 3 years (30.5% in Q1 to 17.0% in Q5, p = 0.003; and 23.9% in Q1 to 9.8% in Q5, p = 0.003, respectively). These trends remained significant after adjusting for clinical characteristics and risk. No significant trend in mortality was observed in patients with LVEF ≥ 50%. In a cohort of real-life ambulatory patients with HF, mortality progressively declined in patients with LVEF < 50%, but the same trend was not observed in patients with preserved LVEF.Giosafat SpitaleriJosep LupónMar DomingoEvelyn Santiago-VacasPau CodinaElisabet ZamoraGermán CedielJavier SantesmasesCrisanto Diez-QuevedoMaria Isabel TroyaMaria BoldoSalvador AltmirNuria AlonsoBeatriz GonzálezJulio NúñezAntoni Bayes-GenisNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Giosafat Spitaleri Josep Lupón Mar Domingo Evelyn Santiago-Vacas Pau Codina Elisabet Zamora Germán Cediel Javier Santesmases Crisanto Diez-Quevedo Maria Isabel Troya Maria Boldo Salvador Altmir Nuria Alonso Beatriz González Julio Núñez Antoni Bayes-Genis Mortality trends in an ambulatory multidisciplinary heart failure unit from 2001 to 2018
description	Abstract To assess mortality trends at 1 and 3 years from 2001 to 2018 in a real-life cohort of HF outpatients from different etiologies with depressed and preserved LVEF. A total of 2368 consecutive patients with HF (mean age 66.4 ± 12.9 years, 71% men, 15.4% with preserved LVEF) admitted to a HF clinic from August 2001 to September 2018 were included in the study. Patients were divided into five quintiles (Q) according to the period of admission. Trends for all-cause and cardiovascular mortality from Q1 to Q5 were assessed by linear regression. Patients with LVEF < 50% had a progressive decrease in the rates of all-cause and cardiovascular death at 1 year (12.1% in Q1 to 6.5% in Q5, p = 0.003; and 8.4% in Q1 to 3.8% in Q5, p = 0.007, respectively) and 3 years (30.5% in Q1 to 17.0% in Q5, p = 0.003; and 23.9% in Q1 to 9.8% in Q5, p = 0.003, respectively). These trends remained significant after adjusting for clinical characteristics and risk. No significant trend in mortality was observed in patients with LVEF ≥ 50%. In a cohort of real-life ambulatory patients with HF, mortality progressively declined in patients with LVEF < 50%, but the same trend was not observed in patients with preserved LVEF.
format	article
author	Giosafat Spitaleri Josep Lupón Mar Domingo Evelyn Santiago-Vacas Pau Codina Elisabet Zamora Germán Cediel Javier Santesmases Crisanto Diez-Quevedo Maria Isabel Troya Maria Boldo Salvador Altmir Nuria Alonso Beatriz González Julio Núñez Antoni Bayes-Genis
author_facet	Giosafat Spitaleri Josep Lupón Mar Domingo Evelyn Santiago-Vacas Pau Codina Elisabet Zamora Germán Cediel Javier Santesmases Crisanto Diez-Quevedo Maria Isabel Troya Maria Boldo Salvador Altmir Nuria Alonso Beatriz González Julio Núñez Antoni Bayes-Genis
author_sort	Giosafat Spitaleri
title	Mortality trends in an ambulatory multidisciplinary heart failure unit from 2001 to 2018
title_short	Mortality trends in an ambulatory multidisciplinary heart failure unit from 2001 to 2018
title_full	Mortality trends in an ambulatory multidisciplinary heart failure unit from 2001 to 2018
title_fullStr	Mortality trends in an ambulatory multidisciplinary heart failure unit from 2001 to 2018
title_full_unstemmed	Mortality trends in an ambulatory multidisciplinary heart failure unit from 2001 to 2018
title_sort	mortality trends in an ambulatory multidisciplinary heart failure unit from 2001 to 2018
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/e5c30ec096344f0da1e3b50ea1f295d2
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Mortality trends in an ambulatory multidisciplinary heart failure unit from 2001 to 2018

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