Chronic alcohol exposure disrupts top-down control over basal ganglia action selection to produce habits

Drug dependence shifts the balance in action selection away from goal-directed to habitual responding. Here, the authors report that chronic passive exposure to alcohol leads to suppression of orbitofrontal cortex inputs to dorsomedial striatum resulting in downregulation of goal-directed behavior.

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Detalles Bibliográficos
Autores principales: Rafael Renteria, Emily T. Baltz, Christina M. Gremel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/e5cd28663bd242ea9e1ab8a47e9caa49
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