Histone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome

Hirano et al. show that the H2A.B-H2B histone dimer incorporated within the nucleosome exchanges with the canonical H2A-H2B dimer without assistance from histone chaperones or nucleosome remodelers. This study provides insights into how the H2A.B nucleosome exchanges its histones.

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Autores principales: Rina Hirano, Yasuhiro Arimura, Tomoya Kujirai, Mikihiro Shibata, Aya Okuda, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Hitoshi Kurumizaka
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e5db19da91414c99b864481c4f745c6e
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spelling oai:doaj.org-article:e5db19da91414c99b864481c4f745c6e2021-12-02T14:26:53ZHistone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome10.1038/s42003-021-01707-z2399-3642https://doaj.org/article/e5db19da91414c99b864481c4f745c6e2021-02-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01707-zhttps://doaj.org/toc/2399-3642Hirano et al. show that the H2A.B-H2B histone dimer incorporated within the nucleosome exchanges with the canonical H2A-H2B dimer without assistance from histone chaperones or nucleosome remodelers. This study provides insights into how the H2A.B nucleosome exchanges its histones.Rina HiranoYasuhiro ArimuraTomoya KujiraiMikihiro ShibataAya OkudaKen MorishimaRintaro InoueMasaaki SugiyamaHitoshi KurumizakaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Rina Hirano
Yasuhiro Arimura
Tomoya Kujirai
Mikihiro Shibata
Aya Okuda
Ken Morishima
Rintaro Inoue
Masaaki Sugiyama
Hitoshi Kurumizaka
Histone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome
description Hirano et al. show that the H2A.B-H2B histone dimer incorporated within the nucleosome exchanges with the canonical H2A-H2B dimer without assistance from histone chaperones or nucleosome remodelers. This study provides insights into how the H2A.B nucleosome exchanges its histones.
format article
author Rina Hirano
Yasuhiro Arimura
Tomoya Kujirai
Mikihiro Shibata
Aya Okuda
Ken Morishima
Rintaro Inoue
Masaaki Sugiyama
Hitoshi Kurumizaka
author_facet Rina Hirano
Yasuhiro Arimura
Tomoya Kujirai
Mikihiro Shibata
Aya Okuda
Ken Morishima
Rintaro Inoue
Masaaki Sugiyama
Hitoshi Kurumizaka
author_sort Rina Hirano
title Histone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome
title_short Histone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome
title_full Histone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome
title_fullStr Histone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome
title_full_unstemmed Histone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome
title_sort histone variant h2a.b-h2b dimers are spontaneously exchanged with canonical h2a-h2b in the nucleosome
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/e5db19da91414c99b864481c4f745c6e
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