Influencing Factors and Prevention of Sepsis or Acute Kidney Injury in 85 Patients with Severe Trauma

Severe trauma can cause systemic reactions, leading to massive bleeding, shock, asphyxia, and disturbance of consciousness. At the same time, patients with severe trauma are at high risk of sepsis and acute renal injury. The occurrence of complications will increase the difficulty of clinical treatm...

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Autores principales: Hong Zhang, Dan Chen, Lihua Wang, Bing Li
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Lenguaje:EN
Publicado: Hindawi Limited 2021
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Acceso en línea:https://doaj.org/article/e5e09132193f4b759f8033cc516cd7e8
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spelling oai:doaj.org-article:e5e09132193f4b759f8033cc516cd7e82021-11-15T01:20:04ZInfluencing Factors and Prevention of Sepsis or Acute Kidney Injury in 85 Patients with Severe Trauma1741-428810.1155/2021/5754114https://doaj.org/article/e5e09132193f4b759f8033cc516cd7e82021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/5754114https://doaj.org/toc/1741-4288Severe trauma can cause systemic reactions, leading to massive bleeding, shock, asphyxia, and disturbance of consciousness. At the same time, patients with severe trauma are at high risk of sepsis and acute renal injury. The occurrence of complications will increase the difficulty of clinical treatment, improve the mortality rate, and bring heavy physical and mental burdens and economic pressure to patients and their families. It is of great clinical significance to understand the high risk factors of sepsis and AKI and actively formulate prevention and treatment measures. In this study, the clinical data of 85 patients with severe trauma were analyzed by univariate and multivariate logistic regression to identify the risk factors leading to sepsis or AKI and analyze the prevention and treatment strategies. The results showed that multiple injuries, APACHE II score on admission, SOFA score on admission, and mechanical ventilation were independent influencing factors of sepsis in patients with severe trauma, while hemorrhagic shock, APACHE II score on admission, CRRT, and sepsis were independent influencing factors of AKI in patients with severe trauma. Severe trauma patients complicated with sepsis or AKI will increase the risk of death. In the course of treatment, prevention and intervention should be given as far as possible to reduce the incidence of complications.Hong ZhangDan ChenLihua WangBing LiHindawi LimitedarticleOther systems of medicineRZ201-999ENEvidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
institution DOAJ
collection DOAJ
language EN
topic Other systems of medicine
RZ201-999
spellingShingle Other systems of medicine
RZ201-999
Hong Zhang
Dan Chen
Lihua Wang
Bing Li
Influencing Factors and Prevention of Sepsis or Acute Kidney Injury in 85 Patients with Severe Trauma
description Severe trauma can cause systemic reactions, leading to massive bleeding, shock, asphyxia, and disturbance of consciousness. At the same time, patients with severe trauma are at high risk of sepsis and acute renal injury. The occurrence of complications will increase the difficulty of clinical treatment, improve the mortality rate, and bring heavy physical and mental burdens and economic pressure to patients and their families. It is of great clinical significance to understand the high risk factors of sepsis and AKI and actively formulate prevention and treatment measures. In this study, the clinical data of 85 patients with severe trauma were analyzed by univariate and multivariate logistic regression to identify the risk factors leading to sepsis or AKI and analyze the prevention and treatment strategies. The results showed that multiple injuries, APACHE II score on admission, SOFA score on admission, and mechanical ventilation were independent influencing factors of sepsis in patients with severe trauma, while hemorrhagic shock, APACHE II score on admission, CRRT, and sepsis were independent influencing factors of AKI in patients with severe trauma. Severe trauma patients complicated with sepsis or AKI will increase the risk of death. In the course of treatment, prevention and intervention should be given as far as possible to reduce the incidence of complications.
format article
author Hong Zhang
Dan Chen
Lihua Wang
Bing Li
author_facet Hong Zhang
Dan Chen
Lihua Wang
Bing Li
author_sort Hong Zhang
title Influencing Factors and Prevention of Sepsis or Acute Kidney Injury in 85 Patients with Severe Trauma
title_short Influencing Factors and Prevention of Sepsis or Acute Kidney Injury in 85 Patients with Severe Trauma
title_full Influencing Factors and Prevention of Sepsis or Acute Kidney Injury in 85 Patients with Severe Trauma
title_fullStr Influencing Factors and Prevention of Sepsis or Acute Kidney Injury in 85 Patients with Severe Trauma
title_full_unstemmed Influencing Factors and Prevention of Sepsis or Acute Kidney Injury in 85 Patients with Severe Trauma
title_sort influencing factors and prevention of sepsis or acute kidney injury in 85 patients with severe trauma
publisher Hindawi Limited
publishDate 2021
url https://doaj.org/article/e5e09132193f4b759f8033cc516cd7e8
work_keys_str_mv AT hongzhang influencingfactorsandpreventionofsepsisoracutekidneyinjuryin85patientswithseveretrauma
AT danchen influencingfactorsandpreventionofsepsisoracutekidneyinjuryin85patientswithseveretrauma
AT lihuawang influencingfactorsandpreventionofsepsisoracutekidneyinjuryin85patientswithseveretrauma
AT bingli influencingfactorsandpreventionofsepsisoracutekidneyinjuryin85patientswithseveretrauma
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