Identification and functional analysis of Trypanosoma cruzi genes that encode proteins of the glycosylphosphatidylinositol biosynthetic pathway.

Identification and functional analysis of Trypanosoma cruzi genes that encode proteins of the glycosylphosphatidylinositol biosynthetic pathway.

<h4>Background</h4>Trypanosoma cruzi is a protist parasite that causes Chagas disease. Several proteins that are essential for parasite virulence and involved in host immune responses are anchored to the membrane through glycosylphosphatidylinositol (GPI) molecules. In addition, T. cruzi...

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Detalles Bibliográficos
Autores principales: Mariana S Cardoso, Caroline Junqueira, Ricardo C Trigueiro, Hosam Shams-Eldin, Cristiana S Macedo, Patrícia R Araújo, Dawidson A Gomes, Patrícia M Martinelli, Jürgen Kimmel, Philipp Stahl, Sebastian Niehus, Ralph T Schwarz, José O Previato, Lucia Mendonça-Previato, Ricardo T Gazzinelli, Santuza M R Teixeira
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Arctic medicine. Tropical medicine
RC955-962
Public aspects of medicine
RA1-1270
Acceso en línea:https://doaj.org/article/e5ee87b733a04651b11e02fe89010bff
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