PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens

Despite the importance of pharmacological and functional genomic screens the readouts are of low complexity. Here the authors introduce PLATE-Seq, a low-cost genome-wide mRNA profiling method to complement high-throughput screening.

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Autores principales:	Erin C. Bush, Forest Ray, Mariano J. Alvarez, Ronald Realubit, Hai Li, Charles Karan, Andrea Califano, Peter A. Sims
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e5f52de1917b45b2852cf14b048734c5
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spelling	oai:doaj.org-article:e5f52de1917b45b2852cf14b048734c52021-12-02T13:24:05ZPLATE-Seq for genome-wide regulatory network analysis of high-throughput screens10.1038/s41467-017-00136-z2041-1723https://doaj.org/article/e5f52de1917b45b2852cf14b048734c52017-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00136-zhttps://doaj.org/toc/2041-1723Despite the importance of pharmacological and functional genomic screens the readouts are of low complexity. Here the authors introduce PLATE-Seq, a low-cost genome-wide mRNA profiling method to complement high-throughput screening.Erin C. BushForest RayMariano J. AlvarezRonald RealubitHai LiCharles KaranAndrea CalifanoPeter A. SimsNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Erin C. Bush Forest Ray Mariano J. Alvarez Ronald Realubit Hai Li Charles Karan Andrea Califano Peter A. Sims PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens
description	Despite the importance of pharmacological and functional genomic screens the readouts are of low complexity. Here the authors introduce PLATE-Seq, a low-cost genome-wide mRNA profiling method to complement high-throughput screening.
format	article
author	Erin C. Bush Forest Ray Mariano J. Alvarez Ronald Realubit Hai Li Charles Karan Andrea Califano Peter A. Sims
author_facet	Erin C. Bush Forest Ray Mariano J. Alvarez Ronald Realubit Hai Li Charles Karan Andrea Califano Peter A. Sims
author_sort	Erin C. Bush
title	PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens
title_short	PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens
title_full	PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens
title_fullStr	PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens
title_full_unstemmed	PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens
title_sort	plate-seq for genome-wide regulatory network analysis of high-throughput screens
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e5f52de1917b45b2852cf14b048734c5
work_keys_str_mv	AT erincbush plateseqforgenomewideregulatorynetworkanalysisofhighthroughputscreens AT forestray plateseqforgenomewideregulatorynetworkanalysisofhighthroughputscreens AT marianojalvarez plateseqforgenomewideregulatorynetworkanalysisofhighthroughputscreens AT ronaldrealubit plateseqforgenomewideregulatorynetworkanalysisofhighthroughputscreens AT haili plateseqforgenomewideregulatorynetworkanalysisofhighthroughputscreens AT charleskaran plateseqforgenomewideregulatorynetworkanalysisofhighthroughputscreens AT andreacalifano plateseqforgenomewideregulatorynetworkanalysisofhighthroughputscreens AT peterasims plateseqforgenomewideregulatorynetworkanalysisofhighthroughputscreens
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PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens

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