Discovery of rare cells from voluminous single cell expression data

Algorithms designed to find rare cells in single cell RNA-seq data sets cannot cope with data sets containing tens of thousands of cells. Here the authors present Finder of Rare Entities (FiRE), an algorithm that uses the Sketching technique to assign a rareness score to every expression profile in...

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Autores principales: Aashi Jindal, Prashant Gupta, Jayadeva, Debarka Sengupta
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/e5f61881b96d473a964962f81525ffb9
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spelling oai:doaj.org-article:e5f61881b96d473a964962f81525ffb92021-12-02T17:32:47ZDiscovery of rare cells from voluminous single cell expression data10.1038/s41467-018-07234-62041-1723https://doaj.org/article/e5f61881b96d473a964962f81525ffb92018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07234-6https://doaj.org/toc/2041-1723Algorithms designed to find rare cells in single cell RNA-seq data sets cannot cope with data sets containing tens of thousands of cells. Here the authors present Finder of Rare Entities (FiRE), an algorithm that uses the Sketching technique to assign a rareness score to every expression profile in large RNA-seq data sets.Aashi JindalPrashant GuptaJayadevaDebarka SenguptaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Aashi Jindal
Prashant Gupta
Jayadeva
Debarka Sengupta
Discovery of rare cells from voluminous single cell expression data
description Algorithms designed to find rare cells in single cell RNA-seq data sets cannot cope with data sets containing tens of thousands of cells. Here the authors present Finder of Rare Entities (FiRE), an algorithm that uses the Sketching technique to assign a rareness score to every expression profile in large RNA-seq data sets.
format article
author Aashi Jindal
Prashant Gupta
Jayadeva
Debarka Sengupta
author_facet Aashi Jindal
Prashant Gupta
Jayadeva
Debarka Sengupta
author_sort Aashi Jindal
title Discovery of rare cells from voluminous single cell expression data
title_short Discovery of rare cells from voluminous single cell expression data
title_full Discovery of rare cells from voluminous single cell expression data
title_fullStr Discovery of rare cells from voluminous single cell expression data
title_full_unstemmed Discovery of rare cells from voluminous single cell expression data
title_sort discovery of rare cells from voluminous single cell expression data
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/e5f61881b96d473a964962f81525ffb9
work_keys_str_mv AT aashijindal discoveryofrarecellsfromvoluminoussinglecellexpressiondata
AT prashantgupta discoveryofrarecellsfromvoluminoussinglecellexpressiondata
AT jayadeva discoveryofrarecellsfromvoluminoussinglecellexpressiondata
AT debarkasengupta discoveryofrarecellsfromvoluminoussinglecellexpressiondata
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