Combining Mutations That Inhibit Two Distinct Steps of the ATP Hydrolysis Cycle Restores Wild-Type Function in the Lipopolysaccharide Transporter and Shows that ATP Binding Triggers Transport
ABSTRACT ATP-binding cassette (ABC) transporters constitute a large family of proteins present in all domains of life. They are powered by dynamic ATPases that harness energy from binding and hydrolyzing ATP through a cycle that involves the closing and reopening of their two ATP-binding domains. Th...
Enregistré dans:
Auteurs principaux: | Brent W. Simpson, Karanbir S. Pahil, Tristan W. Owens, Emily A. Lundstedt, Rebecca M. Davis, Daniel Kahne, Natividad Ruiz |
---|---|
Format: | article |
Langue: | EN |
Publié: |
American Society for Microbiology
2019
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/e5f9ae4be9c9430f83be36fa788bf4ff |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
An ATP-Binding Cassette Transporter, LaABCB11, Contributes to Alkaloid Transport in <i>Lycoris aurea</i>
par: Rong Wang, et autres
Publié: (2021) -
The Function and Expression of ATP-Binding Cassette Transporters Proteins in the Alzheimer's Disease
par: Asli Aykac, et autres
Publié: (2021) -
Synthesis of Aminooxy Glycoside Derivatives of the Outer Core Domain of Pseudomonas aeruginosa Lipopolysaccharide
par: Anshupriya Si, et autres
Publié: (2021) -
Conformational motion of the ABC transporter MsbA induced by ATP hydrolysis.
par: Peter P Borbat, et autres
Publié: (2007) -
Identification of Residues in the Lipopolysaccharide ABC Transporter That Coordinate ATPase Activity with Extractor Function
par: Brent W. Simpson, et autres
Publié: (2016)