Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns

Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns

Folic acid is routinely recommended for women trying to conceive to ensure proper fetal development. Here, the authors perform a large epigenomics study to examine which fetal epigenetic changes are associated with varied maternal plasma folate levels.

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Detalles Bibliográficos
Autores principales: Bonnie R. Joubert, Herman T. den Dekker, Janine F. Felix, Jon Bohlin, Symen Ligthart, Emma Beckett, Henning Tiemeier, Joyce B. van Meurs, Andre G. Uitterlinden, Albert Hofman, Siri E. Håberg, Sarah E. Reese, Marjolein J. Peters, Bettina Kulle Andreassen, Eric A. P. Steegers, Roy M. Nilsen, Stein E. Vollset, Øivind Midttun, Per M. Ueland, Oscar H. Franco, Abbas Dehghan, Johan C. de Jongste, Michael C. Wu, Tianyuan Wang, Shyamal D. Peddada, Vincent W. V. Jaddoe, Wenche Nystad, Liesbeth Duijts, Stephanie J. London
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/e5fa74991c5c4717866da34246f9c423
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Descripción
Sumario:Folic acid is routinely recommended for women trying to conceive to ensure proper fetal development. Here, the authors perform a large epigenomics study to examine which fetal epigenetic changes are associated with varied maternal plasma folate levels.

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