Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns
Folic acid is routinely recommended for women trying to conceive to ensure proper fetal development. Here, the authors perform a large epigenomics study to examine which fetal epigenetic changes are associated with varied maternal plasma folate levels.
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2016
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/e5fa74991c5c4717866da34246f9c423 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:e5fa74991c5c4717866da34246f9c423 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:e5fa74991c5c4717866da34246f9c4232021-12-02T17:32:39ZMaternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns10.1038/ncomms105772041-1723https://doaj.org/article/e5fa74991c5c4717866da34246f9c4232016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10577https://doaj.org/toc/2041-1723Folic acid is routinely recommended for women trying to conceive to ensure proper fetal development. Here, the authors perform a large epigenomics study to examine which fetal epigenetic changes are associated with varied maternal plasma folate levels.Bonnie R. JoubertHerman T. den DekkerJanine F. FelixJon BohlinSymen LigthartEmma BeckettHenning TiemeierJoyce B. van MeursAndre G. UitterlindenAlbert HofmanSiri E. HåbergSarah E. ReeseMarjolein J. PetersBettina Kulle AndreassenEric A. P. SteegersRoy M. NilsenStein E. VollsetØivind MidttunPer M. UelandOscar H. FrancoAbbas DehghanJohan C. de JongsteMichael C. WuTianyuan WangShyamal D. PeddadaVincent W. V. JaddoeWenche NystadLiesbeth DuijtsStephanie J. LondonNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Bonnie R. Joubert Herman T. den Dekker Janine F. Felix Jon Bohlin Symen Ligthart Emma Beckett Henning Tiemeier Joyce B. van Meurs Andre G. Uitterlinden Albert Hofman Siri E. Håberg Sarah E. Reese Marjolein J. Peters Bettina Kulle Andreassen Eric A. P. Steegers Roy M. Nilsen Stein E. Vollset Øivind Midttun Per M. Ueland Oscar H. Franco Abbas Dehghan Johan C. de Jongste Michael C. Wu Tianyuan Wang Shyamal D. Peddada Vincent W. V. Jaddoe Wenche Nystad Liesbeth Duijts Stephanie J. London Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns |
| description |
Folic acid is routinely recommended for women trying to conceive to ensure proper fetal development. Here, the authors perform a large epigenomics study to examine which fetal epigenetic changes are associated with varied maternal plasma folate levels. |
| format |
article |
| author |
Bonnie R. Joubert Herman T. den Dekker Janine F. Felix Jon Bohlin Symen Ligthart Emma Beckett Henning Tiemeier Joyce B. van Meurs Andre G. Uitterlinden Albert Hofman Siri E. Håberg Sarah E. Reese Marjolein J. Peters Bettina Kulle Andreassen Eric A. P. Steegers Roy M. Nilsen Stein E. Vollset Øivind Midttun Per M. Ueland Oscar H. Franco Abbas Dehghan Johan C. de Jongste Michael C. Wu Tianyuan Wang Shyamal D. Peddada Vincent W. V. Jaddoe Wenche Nystad Liesbeth Duijts Stephanie J. London |
| author_facet |
Bonnie R. Joubert Herman T. den Dekker Janine F. Felix Jon Bohlin Symen Ligthart Emma Beckett Henning Tiemeier Joyce B. van Meurs Andre G. Uitterlinden Albert Hofman Siri E. Håberg Sarah E. Reese Marjolein J. Peters Bettina Kulle Andreassen Eric A. P. Steegers Roy M. Nilsen Stein E. Vollset Øivind Midttun Per M. Ueland Oscar H. Franco Abbas Dehghan Johan C. de Jongste Michael C. Wu Tianyuan Wang Shyamal D. Peddada Vincent W. V. Jaddoe Wenche Nystad Liesbeth Duijts Stephanie J. London |
| author_sort |
Bonnie R. Joubert |
| title |
Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns |
| title_short |
Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns |
| title_full |
Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns |
| title_fullStr |
Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns |
| title_full_unstemmed |
Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns |
| title_sort |
maternal plasma folate impacts differential dna methylation in an epigenome-wide meta-analysis of newborns |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/e5fa74991c5c4717866da34246f9c423 |
| work_keys_str_mv |
AT bonnierjoubert maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT hermantdendekker maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT janineffelix maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT jonbohlin maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT symenligthart maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT emmabeckett maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT henningtiemeier maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT joycebvanmeurs maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT andreguitterlinden maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT alberthofman maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT siriehaberg maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT sarahereese maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT marjoleinjpeters maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT bettinakulleandreassen maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT ericapsteegers maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT roymnilsen maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT steinevollset maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT øivindmidttun maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT permueland maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT oscarhfranco maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT abbasdehghan maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT johancdejongste maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT michaelcwu maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT tianyuanwang maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT shyamaldpeddada maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT vincentwvjaddoe maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT wenchenystad maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT liesbethduijts maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns AT stephaniejlondon maternalplasmafolateimpactsdifferentialdnamethylationinanepigenomewidemetaanalysisofnewborns |
| _version_ |
1718380281451249664 |