Sensing intracellular calcium ions using a manganese-based MRI contrast agent

Sensing intracellular calcium ions using a manganese-based MRI contrast agent

There are only few MRI-compatible calcium reporters and they are limited to measuring extracellular calcium levels. Here the authors develop and validate a cell-permeable, manganese-based paramagnetic MRI contrast agent that enables monitoring intracellular calcium signals in vivo in the rat brain.

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Detalles Bibliográficos
Autores principales: Ali Barandov, Benjamin B. Bartelle, Catherine G. Williamson, Emily S. Loucks, Stephen J. Lippard, Alan Jasanoff
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
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Acceso en línea:https://doaj.org/article/e5faf82e358e48b88a58d6f635d5f18c
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