Variation of basal EROD activities in ten passerine bird species--relationships with diet and migration status.

Inter-specific differences in animal defence mechanisms against toxic substances are currently poorly understood. The ethoxyresorufin-O-deethylase (EROD) enzyme plays an important role in defence against toxic chemicals in a wide variety of animals, and it is an important biomarker for environmental...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Miia J Rainio, Mirella Kanerva, Niklas Wahlberg, Mikko Nikinmaa, Tapio Eeva
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/e5fb250bcd314301a7474ed9ccfce1a2
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e5fb250bcd314301a7474ed9ccfce1a2
record_format	dspace
spelling	oai:doaj.org-article:e5fb250bcd314301a7474ed9ccfce1a22021-11-18T07:23:52ZVariation of basal EROD activities in ten passerine bird species--relationships with diet and migration status.1932-620310.1371/journal.pone.0033926https://doaj.org/article/e5fb250bcd314301a7474ed9ccfce1a22012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22479477/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Inter-specific differences in animal defence mechanisms against toxic substances are currently poorly understood. The ethoxyresorufin-O-deethylase (EROD) enzyme plays an important role in defence against toxic chemicals in a wide variety of animals, and it is an important biomarker for environmental contamination. We compared basal hepatic EROD activity levels among ten passerine species to see if there is inter-specific variation in enzyme activity, especially in relation to their diet and migration status. Migratory insectivores showed higher EROD activity compared to granivores. We hypothesize that the variable invertebrate diet of migratory insectivores contains a wider range of natural toxins than the narrower diet of granivores. This may have affected the evolution of mixed function oxidases (MFO) system and enzyme activities. We further tested whether metabolic rates or relative liver size were associated with the variation in detoxification capacity. We found no association between EROD activity and relative (per mass unit) basal metabolic rate (BMR). Instead, EROD activity and relative liver mass (% of body mass) correlated positively, suggesting that a proportionally large liver also functions efficiently. Our results suggest that granivores and non-migratory birds may be more vulnerable to environmental contaminants than insectivores and migratory birds. The diet and migration status, however, are phylogenetically strongly connected to each other, and their roles cannot be fully separated in our analysis with only ten passerine species.Miia J RainioMirella KanervaNiklas WahlbergMikko NikinmaaTapio EevaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 3, p e33926 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Miia J Rainio Mirella Kanerva Niklas Wahlberg Mikko Nikinmaa Tapio Eeva Variation of basal EROD activities in ten passerine bird species--relationships with diet and migration status.
description	Inter-specific differences in animal defence mechanisms against toxic substances are currently poorly understood. The ethoxyresorufin-O-deethylase (EROD) enzyme plays an important role in defence against toxic chemicals in a wide variety of animals, and it is an important biomarker for environmental contamination. We compared basal hepatic EROD activity levels among ten passerine species to see if there is inter-specific variation in enzyme activity, especially in relation to their diet and migration status. Migratory insectivores showed higher EROD activity compared to granivores. We hypothesize that the variable invertebrate diet of migratory insectivores contains a wider range of natural toxins than the narrower diet of granivores. This may have affected the evolution of mixed function oxidases (MFO) system and enzyme activities. We further tested whether metabolic rates or relative liver size were associated with the variation in detoxification capacity. We found no association between EROD activity and relative (per mass unit) basal metabolic rate (BMR). Instead, EROD activity and relative liver mass (% of body mass) correlated positively, suggesting that a proportionally large liver also functions efficiently. Our results suggest that granivores and non-migratory birds may be more vulnerable to environmental contaminants than insectivores and migratory birds. The diet and migration status, however, are phylogenetically strongly connected to each other, and their roles cannot be fully separated in our analysis with only ten passerine species.
format	article
author	Miia J Rainio Mirella Kanerva Niklas Wahlberg Mikko Nikinmaa Tapio Eeva
author_facet	Miia J Rainio Mirella Kanerva Niklas Wahlberg Mikko Nikinmaa Tapio Eeva
author_sort	Miia J Rainio
title	Variation of basal EROD activities in ten passerine bird species--relationships with diet and migration status.
title_short	Variation of basal EROD activities in ten passerine bird species--relationships with diet and migration status.
title_full	Variation of basal EROD activities in ten passerine bird species--relationships with diet and migration status.
title_fullStr	Variation of basal EROD activities in ten passerine bird species--relationships with diet and migration status.
title_full_unstemmed	Variation of basal EROD activities in ten passerine bird species--relationships with diet and migration status.
title_sort	variation of basal erod activities in ten passerine bird species--relationships with diet and migration status.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/e5fb250bcd314301a7474ed9ccfce1a2
work_keys_str_mv	AT miiajrainio variationofbasalerodactivitiesintenpasserinebirdspeciesrelationshipswithdietandmigrationstatus AT mirellakanerva variationofbasalerodactivitiesintenpasserinebirdspeciesrelationshipswithdietandmigrationstatus AT niklaswahlberg variationofbasalerodactivitiesintenpasserinebirdspeciesrelationshipswithdietandmigrationstatus AT mikkonikinmaa variationofbasalerodactivitiesintenpasserinebirdspeciesrelationshipswithdietandmigrationstatus AT tapioeeva variationofbasalerodactivitiesintenpasserinebirdspeciesrelationshipswithdietandmigrationstatus
_version_	1718423569438867456

Variation of basal EROD activities in ten passerine bird species--relationships with diet and migration status.

Ejemplares similares